Functional recovery from peripheral nerve injury and repair depends on a multitude of
factors, both intrinsic and extrinsic to neurons. Neuronal survival after axotomy is a …

Whereas the central nervous system (CNS) usually cannot regenerate, peripheral nerves
regenerate spontaneously after injury because of a permissive environment and activation …

Cytokines are a heterogeneous group of polypeptide mediators that have been aswciakd
classically wlth activation of the lmmune system and inflammatory responses. An incmasing …

Peripheral human nerves fail to regenerate across longer tube implants (> 2cm), most likely
because implants lack the microarchitecture of native nerves, including bands of Büngner …

Microglia represent a major cellular component of the brain, where they constitute a widely
distributed network of immunoprotective cells. During the last decades, it has become clear …

The basic pathophysiology of nerve compression injuries is complex and it is important to
consider the microanatomy of the neuron and the peripheral nerve. The clinical stages of …

RNA from rat dorsal root ganglia was analyzed in search of potentially beneficial cytokines
that are induced in dorsal root ganglia by nerve injury. By reverse transcription, the PCR …

Representing the treatment and management philosophy of Dr. Susan Mackinnon, Nerve
Surgery provides extensive coverage of innovative surgical options as well as guidance on …

Recent experiments in neural, skeletal, endothelial, and hematopoietic tissues have
provided new insights into the way members of the transforming growth factor-β (TGF-β) …

Following peripheral nerve injury, remnant Schwann cells adopt a migratory phenotype and
remodel the extracellular matrix allowing axonal regrowth. Although much evidence has …