Carbohydrates are essential mediators of many processes in health and disease. They
regulate self-/non-self-discrimination, are key elements of cellular communication, cancer …

In recent years, infectious diseases have again become a critical threat to global public
health largely due to the challenges posed by antimicrobial resistance. Conventional …

Chronic Pseudomonas aeruginosa infections are characterized by biofilm formation, a major
virulence factor of P. aeruginosa and cause of extensive drug resistance. Fluoroquinolones …

Bacterial adhesion, biofilm formation and host cell invasion of the ESKAPE pathogen
Pseudomonas aeruginosa require the tetravalent lectins LecA and LecB, which are …

The Gram-negative pathogen Pseudomonas aeruginosa causes severe infections mainly in
immunocompromised or cystic fibrosis patients and is able to resist antimicrobial treatments …

In their role as pattern-recognition receptors on cells of the innate immune system, myeloid
C-type lectin receptors (CLRs) assume important biological functions related to immunity …

Carbohydrate-protein interactions are key for cell-cell and host-pathogen recognition and
thus, emerged as viable therapeutic targets. However, their hydrophilic nature poses major …

Pseudomonas aeruginosa is an opportunistic human pathogen responsible for acute and
chronic, hard to treat infections. Persistence of P. aeruginosa is due to its ability to develop …

The antimicrobial resistance crisis requires novel approaches for the therapy of infections
especially with Gram-negative pathogens. Pseudomonas aeruginosa is defined as priority 1 …

Pseudomonas aeruginosa is a pathogenic bacterium, responsible for a large portion of
nosocomial infections globally and designated as critical priority by the World Health …