The risk assessment of chemical carcinogens is one major task in toxicology. Even though
exposure has been mitigated effectively during the last decades, low levels of carcinogenic …

One of the most commonly known genes involved in chronic diffuse liver diseases
pathogenesis are genes that encodes the synthesis of glutathione-S-transferase (GST) …

Plant hormones and antioxidant system changes occur during plants' exposure to stress
conditions. Although the interactions of some plant hormones (abscisic acid, salicylic acid …

Several studies linked between pesticides exposure and development of liver cancer,
through several mechanisms inform of genotoxicity, cytotoxicity, tumor promotion …

BACKGROUND/AIMS Biological and epidemiological data suggest that vitamin D levels
may influence cancer development. Several single nucleotide polymorphisms have been …

We aimed to determine whether aflatoxin dietary exposure plays a role in the high incidence
of hepatocellular carcinoma (HCC) observed among Hispanics in South Texas. We …

Chronic alcohol and tobacco abuse plays a crucial role in the development of different liver
associated disorders. Intake promotes the generation of reactive oxygen species within …

Glutathione S-transferases (GSTs) detoxify toxic molecules by conjugation with reduced
glutathione and regulate cell signaling. Single nucleotide polymorphisms (SNPs) of GST …

Background The genetic polymorphisms of glutathione S-transferase (GSTs) have been
suspected to be related to the development of lung cancer while the current results are …

Glutathione S-transferases (GSTs) contribute to the metabolism of different xenobiotics and
anticancer drugs and confer protection against oxidative stress thus may influence the …