Update on overactive bladder therapeutic options

CP Babin, NT Catalano, DM Yancey… - American journal of …, 2024 - journals.lww.com
Background: Millions of Americans are burdened by overactive bladder (OAB) syndrome
and the psychogenic and economic hardships that accompany it. Several theories attempt to …

Acupuncture for women with overactive bladder: perspective of traditional Chinese medicine and related mechanism

H Wang, X Lei - International Journal of General Medicine, 2023 - Taylor & Francis
Purpose Overactive bladder (OAB) syndrome is one of the most common diseases in
urology and affects quality of life. Although the current treatment for OAB is based on oral …

Solifenacin treatment after intradetrusor injections with botulinum toxin in patients with neurogenic detrusor overactivity

I Ciofu, I Ceausu, NM Chirca… - American Journal of …, 2022 - journals.lww.com
Background: Neurogenic detrusor overactivity (NDO) is treated with antimuscarinics as first-
line treatment. For patients with contraindications or unresponsive, intradetrusor injections …

A systematic review and in silico study of potential genetic markers implicated in cases of overactive bladder

I Isali, P McClellan, TR Wong, C Sun, AC Stout… - American journal of …, 2023 - Elsevier
Objective The contribution of genetic factors to the presence of an overactive bladder is
recognized. This study aimed to (1) assemble and synthesize available data from studies …

Medicinal plants and natural products for treating overactive bladder

H Chen, MPM Hoi, SMY Lee - Chinese Medicine, 2024 - Springer
Background Overactive bladder (OAB) presents a high prevalence of 16–18% worldwide.
The pathophysiology of OAB is still poorly understood while effective therapy or …

[HTML][HTML] Genetic Variation in CYP2D6, UGT1A4, SLC6A2 and SLCO1B1 Alters the Pharmacokinetics and Safety of Mirabegron

P Soria-Chacartegui, P Cendoya-Ramiro… - Pharmaceutics, 2024 - mdpi.com
Mirabegron is a drug used in overactive bladder (OAB) treatment. Genetic variation in
pharmacogenes might alter its pharmacokinetics, affecting its efficacy and safety. This …

Cilostazol attenuates mirabegron-induced hepatic and renal toxicity in rats: regulation of metabolic, oxidative, and inflammatory pathways

MM Anwar, IM Ibrahim Laila - Archives of Physiology and …, 2024 - Taylor & Francis
Background Mirabegron (MIRG) is a type of β3 adrenoceptor agonist that is considered an
alternative therapy for the treatment of overactive bladder (OAB) symptoms. Cilostazol (CITZ) …

[HTML][HTML] In Silico Electrophysiological Investigation of Transient Receptor Potential Melastatin-4 Ion Channel Biophysics to Study Detrusor Overactivity

C Mahapatra, R Thakkar - International Journal of Molecular Sciences, 2024 - mdpi.com
Enhanced electrical activity in detrusor smooth muscle (DSM) cells is a key factor in detrusor
overactivity which causes overactive bladder pathological disorders. Transient receptor …

Comprehensive analysis of global research on overactive bladder: a scientometric approach

L Wang, S Deng, F Meng, L Zhang, Z Min, J Li… - Frontiers in …, 2023 - frontiersin.org
Background Overactive bladder, a syndrome marked by an urgent need to urinate, is a
globally prevalent ailment. Human health and quality of life are seriously affected. Therefore …

Association of healthy eating index-2015 and overactive bladder: a cross-sectional study

X Hao, G Liu, D Li - Frontiers in Nutrition, 2024 - frontiersin.org
Objective The aim of this cross-sectional study was to investigate the association of HEI-
2015 and overactive bladder (OAB) in a large population. Methods Data were retrieved from …