The pivotal role of the tumor microenvironment (TME) in the initiation and advancement of
hepatocellular carcinoma (HCC) is widely acknowledged, as it fosters the proliferation and …

A narrative review about the relationship between stress, inflammation, and depression is
made as follows: Chronic stress leads to various stress-related diseases such as …

Microglia-mediated neuroinflammation contributes to acute demyelination in neuromyelitis
optica spectrum disorders (NMOSD). Soluble triggering receptor expressed on myeloid cells …

Neuroinflammation and microglial iron load are significant hallmarks found in several
neurodegenerative diseases. In in vitro systems, microglia preferentially upregulate the iron …

In ischemia-reperfusion stroke, microglia play a dual role in brain injury as well as brain
repair, and promoting their switch from a pro-inflammatory M1 phenotype to an anti …

Fatty acids are metabolized by β‐oxidation within the “mitochondrial ketogenic
pathway”(MKP) to generate β‐hydroxybutyrate (BHB), a ketone body. BHB can be …

Obesity is a key medical challenge of our time. The increasing number of children born to
overweight or obese women is alarming. During pregnancy, the circulation of the mother …

Neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, Multiple
Sclerosis pose substantial public health challenges. While genetics play a primary role …

目的: 探究南极磷虾油对抑郁相关症状的影响. 方法: 采用40mg/L 利血平对斑马鱼(Daniorerio)
进行应激, 诱导斑马鱼抑郁模型, 分别设置空白对照组, 模型组, 氟西汀组, 低剂量磷虾油组和高 …

Intracerebral hemorrhage (ICH) is a severe disease with high mortality. Recently, the role of
BCL-3 in ICH has started to gain attention, but its mechanism remains unclear. A …