The ever-increasing prevalence of noncommunicable diseases (NCDs) represents a major
public health burden worldwide. The most common form of NCD is metabolic diseases …

With the aging of global population, the incidence of nonalcoholic fatty liver disease
(NAFLD) has surged in recent decades. NAFLD is a multifactorial disease that follows a …

Despite the substantial gains in our understanding of NAFLD/NASH over the past 2
decades, there has been some dissatisfaction with the terminology “non‐alcoholic” which …

Exploiting cancer metabolism for the clinical benefit of patients with hepatocellular
carcinoma (HCC) is a topic under active investigation. Ubiquitin-specific peptidase 48 …

Yes-associated protein (YAP) and its paralog, transcriptional coactivator with PDZ-binding
motif (TAZ), play pivotal roles in promoting the progression of hepatocellular carcinoma …

Nonalcoholic fatty liver disease (NAFLD) is characterised by hepatic steatosis, inflammation,
and insulin resistance. The role of long noncoding RNA (lncRNA)-regulated pyroptosis in …

Backgrounds and Aims Activation of hepatic stellate cells (HSCs) is a central driver of
fibrosis. This study aimed to elucidate the role of the deacetylase sirtuin 6 (Sirt6) in HSC …

The water-soluble Morchella esculenta polysaccharide 2 (MEP2) was purified and isolated
from an aqueous extract of the Morchella esculenta fruiting bodies. MEP2, having a …

Nonalcoholic fatty liver disease (NAFLD) is characterized by hepatic steatosis, insulin
resistance, mitochondrial dysfunction, inflammation, and oxidative stress. As a group of …

Ubiquitination and deubiquitination are reversible processes that modify the characteristics
of target proteins, including stability, intracellular localization, and enzymatic activity …