The act of defaecation, although a ubiquitous human experience, requires the coordinated
actions of the anorectum and colon, pelvic floor musculature, and the enteric, peripheral and …

Chronic constipation is a prevalent condition that severely impacts the quality of life of those
affected. Several types of primary chronic constipation, which show substantial overlap …

Our understanding of human colonic motility, and autonomic reflexes that generate motor
patterns, has increased markedly through high-resolution manometry. Details of the motor …

This article is focused on reviewing the current state-of-the-art of optical fibre pressure
sensors for medical applications. Optical fibres have inherent advantages due to their small …

Abstract Background and Purpose Chronic gastric symptoms are common, however
differentiating specific contributing mechanisms in individual patients remains challenging …

Alterations in colonic motility are implicated in the pathophysiology of bowel disorders, but
high-resolution manometry of human colonic motor function has revealed that our …

Chronic constipation is a common, persistent condition affecting many patients worldwide,
presenting significant economic burden and resulting in substantial healthcare utilization. In …

Background Gastric motility disorders, which include both functional and organic etiologies,
are highly prevalent. However, there remains a critical lack of objective biomarkers to guide …

AIM To critically review the literature addressing the definition, epidemiology, aetiology and
pathophysiology of acute colonic pseudo-obstruction (ACPO). METHODS A systematic …

In recent years there have been significant technical and methodological advances in our
ability to record the movements of the gastrointestinal tract. This has led to significant …