Invasive fungal infections (IFIs) represent a growing public concern for clinicians to manage
in many medical settings, with substantial associated morbidities and mortalities. Among …

The development of novel antifungal agents and, in particular, the widespread use of these
medications over the course of the past two decades, has had a significant impact on the …

Highlights•Solid nanoparticles can be used as carriers for antimicrobial drugs.•Provide
better solutions for challenges related to oral antimicrobial drug delivery.•Improve the …

Chronic fungal infection of the cornea could lead to blindness if not treated properly. Topical
amphotericin B (AMP-B) is considered the first treatment of choice for ocular fungal infection …

The liposomal amphotericin B (AmB) formulation, AmBisome®, still represents the best
therapeutic option for cutaneous and visceral leishmaniasis. However, its clinical efficacy …

The physicochemical properties of nanobiomaterials, such as their small size and high
surface area ratio, make them attractive, novel drug-carriers, with increased cellular …

As a neglected tropical disease, Leishmaniasis is significantly instigating morbidity and
mortality across the globe. Its clinical spectrum varies from ulcerative cutaneous lesions to …

Honokiol is a phytochemical component with a variety of pharmacological properties.
However, the major limitation of Honokiol is its poor solubility and low oral bioavailability. In …

Treatment modalities for systemic mycoses are still limited. Currently, the main antifungal
therapeutics include polyenes, azoles, and echinocandins. However, even in the setting of …

The overall aim of this study was to determine whether conjugation with silver nanoparticles
enhances effects of available drugs against primary amoebic meningoencephalitis due to …