Engineering biological nanopore approaches toward protein sequencing
Biotechnological innovations have vastly improved the capacity to perform large-scale
protein studies, while the methods we have for identifying and quantifying individual proteins …
protein studies, while the methods we have for identifying and quantifying individual proteins …
Applications of sequencing technology in clinical microbial infection
X Yu, W Jiang, Y Shi, H Ye, J Lin - Journal of cellular and …, 2019 - Wiley Online Library
Infectious diseases are a type of disease caused by pathogenic microorganisms. Although
the discovery of antibiotics changed the treatment of infectious diseases and reduced the …
the discovery of antibiotics changed the treatment of infectious diseases and reduced the …
Probing DNA translocations with inplane current signals in a graphene nanoribbon with a nanopore
Many theoretical studies predict that DNA sequencing should be feasible by monitoring the
transverse current through a graphene nanoribbon while a DNA molecule translocates …
transverse current through a graphene nanoribbon while a DNA molecule translocates …
Picomolar fingerprinting of nucleic acid nanoparticles using solid-state nanopores
Nucleic acid nanoparticles (NANPs) are an emerging class of programmable structures with
tunable shape and function. Their promise as tools for fundamental biophysics studies …
tunable shape and function. Their promise as tools for fundamental biophysics studies …
Single-molecule recognition of Nucleolin and the interactions with DNA/RNA G-quadruplexes via nanopore decoding
Z Wang, F Qin, J Wu, W Ma, R Li, T Weng, B Yin… - Chemical Engineering …, 2023 - Elsevier
Abstract DNA/RNA quadruplexes (G4) are significant secondary structures that exist in
human genes, playing essential part in transcription and replication. Nucleolin (NCL) is a …
human genes, playing essential part in transcription and replication. Nucleolin (NCL) is a …
High bandwidth approaches in nanopore and ion channel recordings-A tutorial review
Transport processes through ion-channel proteins, protein pores, or solid-state nanopores
are traditionally recorded with commercial patch-clamp amplifiers. The bandwidth of these …
are traditionally recorded with commercial patch-clamp amplifiers. The bandwidth of these …
Discrimination of RNA fiber structures using solid-state nanopores
RNA fibers are a class of biomaterials that can be assembled using HIV-like kissing loop
interactions. Because of the programmability of molecular design and low …
interactions. Because of the programmability of molecular design and low …
A solid‐state hard microfluidic–nanopore biosensor with multilayer fluidics and on‐chip bioassay/purification chamber
N Varongchayakul, JS Hersey… - Advanced functional …, 2018 - Wiley Online Library
Solid‐state nanopores are an emerging biosensor for nucleic acid and protein
characterization. For use in a clinical setting, solid‐state nanopore sensing requires sample …
characterization. For use in a clinical setting, solid‐state nanopore sensing requires sample …
DNA Origami Incorporated into Solid-State Nanopores Enables Enhanced Sensitivity for Precise Analysis of Protein Translocations
The rapidly advancing field of nanotechnology is driving the development of precise sensing
methods at the nanoscale, with solid-state nanopores emerging as promising tools for …
methods at the nanoscale, with solid-state nanopores emerging as promising tools for …
Subangstrom measurements of enzyme function using a biological nanopore, SPRNT
AH Laszlo, IM Derrrington, JH Gundlach - Methods in enzymology, 2017 - Elsevier
Nanopores are emerging as new single-molecule tools in the study of enzymes. Based on
the progress in nanopore sequencing of DNA, a tool called Single-molecule Picometer …
the progress in nanopore sequencing of DNA, a tool called Single-molecule Picometer …