Engineering biological nanopore approaches toward protein sequencing

X Wei, T Penkauskas, JE Reiner, C Kennard… - ACS …, 2023 - ACS Publications
Biotechnological innovations have vastly improved the capacity to perform large-scale
protein studies, while the methods we have for identifying and quantifying individual proteins …

Applications of sequencing technology in clinical microbial infection

X Yu, W Jiang, Y Shi, H Ye, J Lin - Journal of cellular and …, 2019 - Wiley Online Library
Infectious diseases are a type of disease caused by pathogenic microorganisms. Although
the discovery of antibiotics changed the treatment of infectious diseases and reduced the …

Probing DNA translocations with inplane current signals in a graphene nanoribbon with a nanopore

SJ Heerema, L Vicarelli, S Pud, RN Schouten… - ACS …, 2018 - ACS Publications
Many theoretical studies predict that DNA sequencing should be feasible by monitoring the
transverse current through a graphene nanoribbon while a DNA molecule translocates …

Picomolar fingerprinting of nucleic acid nanoparticles using solid-state nanopores

MA Alibakhshi, JR Halman, J Wilson, A Aksimentiev… - ACS …, 2017 - ACS Publications
Nucleic acid nanoparticles (NANPs) are an emerging class of programmable structures with
tunable shape and function. Their promise as tools for fundamental biophysics studies …

Single-molecule recognition of Nucleolin and the interactions with DNA/RNA G-quadruplexes via nanopore decoding

Z Wang, F Qin, J Wu, W Ma, R Li, T Weng, B Yin… - Chemical Engineering …, 2023 - Elsevier
Abstract DNA/RNA quadruplexes (G4) are significant secondary structures that exist in
human genes, playing essential part in transcription and replication. Nucleolin (NCL) is a …

High bandwidth approaches in nanopore and ion channel recordings-A tutorial review

AJW Hartel, S Shekar, P Ong, I Schroeder, G Thiel… - Analytica Chimica …, 2019 - Elsevier
Transport processes through ion-channel proteins, protein pores, or solid-state nanopores
are traditionally recorded with commercial patch-clamp amplifiers. The bandwidth of these …

Discrimination of RNA fiber structures using solid-state nanopores

P Tripathi, M Chandler, CM Maffeo, A Fallahi… - Nanoscale, 2022 - pubs.rsc.org
RNA fibers are a class of biomaterials that can be assembled using HIV-like kissing loop
interactions. Because of the programmability of molecular design and low …

A solid‐state hard microfluidic–nanopore biosensor with multilayer fluidics and on‐chip bioassay/purification chamber

N Varongchayakul, JS Hersey… - Advanced functional …, 2018 - Wiley Online Library
Solid‐state nanopores are an emerging biosensor for nucleic acid and protein
characterization. For use in a clinical setting, solid‐state nanopore sensing requires sample …

DNA Origami Incorporated into Solid-State Nanopores Enables Enhanced Sensitivity for Precise Analysis of Protein Translocations

K Joty, ML Ghimire, JS Kahn, S Lee… - Analytical …, 2024 - ACS Publications
The rapidly advancing field of nanotechnology is driving the development of precise sensing
methods at the nanoscale, with solid-state nanopores emerging as promising tools for …

Subangstrom measurements of enzyme function using a biological nanopore, SPRNT

AH Laszlo, IM Derrrington, JH Gundlach - Methods in enzymology, 2017 - Elsevier
Nanopores are emerging as new single-molecule tools in the study of enzymes. Based on
the progress in nanopore sequencing of DNA, a tool called Single-molecule Picometer …