Recent advances in Bio-conjugated nanocarriers for crossing the Blood-Brain Barrier in (pre-) clinical studies with an emphasis on vesicles

A Poustforoosh, MH Nematollahi… - Journal of Controlled …, 2022 - Elsevier
The brain is one of the most challenging organs for drug delivery. It is preserved by the
blood-brain barrier (BBB), which controls the transport of components into and out of the …

[HTML][HTML] Mitochondrial targeting theranostic nanomedicine and molecular biomarkers for efficient cancer diagnosis and therapy

SK Rout, V Priya, A Setia, AK Mehata, S Mohan… - Biomedicine & …, 2022 - Elsevier
Mitochondria play a crucial part in the cell's ability to adapt to the changing
microenvironments and their dysfunction is associated with an extensive array of illnesses …

Rebirth of aspirin Synthesis By‐Product: Prickly Poly (salicylic acid) nanoparticles as self‐anticancer drug carrier

X You, L Wang, L Wang, J Wu - Advanced Functional Materials, 2021 - Wiley Online Library
As a great drug, aspirin has been used to treat many important diseases. To expand the
biomedical applications of the aspirin material family, in this report, the authors polymerized …

Anti-inflammation-based treatment of atherosclerosis using Gliclazide-loaded biomimetic nanoghosts

Z Karami, J Mehrzad, M Akrami, S Hosseinkhani - Scientific reports, 2023 - nature.com
In the study, a biomimetic platform for anti-inflammatory-based treatment of atherosclerotic
plaque was developed. Gliclazide (GL) as an anti-inflammasome agent was encapsulated in …

Mitochondrial genetic and epigenetic regulations in cancer: therapeutic potential

A Wagner, H Kosnacova, M Chovanec… - International Journal of …, 2022 - mdpi.com
Mitochondria are dynamic organelles managing crucial processes of cellular metabolism
and bioenergetics. Enabling rapid cellular adaptation to altered endogenous and …

[HTML][HTML] Anticancer and microbial activities of gold nanoparticles: A mechanistic review

NH Aljarba, S Imtiaz, N Anwar, IS Alanazi… - Journal of King Saud …, 2022 - Elsevier
According to WHO reports, the emergence of antibiotic resistance together with limited
discovery of newer and effective anticancer and antimicrobial chemotherapeutics remained …

Atherosclerosis: Conventional intake of cardiovascular drugs versus delivery using nanotechnology–A new chance for causative therapy?

J Groner, A Goepferich, M Breunig - Journal of Controlled Release, 2021 - Elsevier
Atherosclerosis is the leading cause of death in developed countries. The pathogenetic
mechanism relies on a macrophage-based immune reaction to low density lipoprotein (LDL) …

Nanozyme enhanced paper-based biochip with a smartphone readout system for rapid detection of cyanotoxins in water

J Liu, Y Xing, B Xue, X Zhou - Biosensors and Bioelectronics, 2022 - Elsevier
Cyanobacterial harmful algal blooms in freshwater systems can produce cyanotoxins, such
as microcystins (MCs) and nodularins (NODs), presenting serious threats to human health …

Recent trends and advances in novel formulations as an armament in Bcl-2/Bax targeted breast cancer

S Samia, PS Chary, O Khan, NK Mehra - International Journal of …, 2024 - Elsevier
Breast cancer (BC) remains a significant health burden worldwide, necessitating the
development of innovative therapeutic strategies. The B-cell lymphoma 2 (Bcl-2) family …

Size-dependent bioactivity of electrosprayed core–shell chitosan-alginate particles for protein delivery

S Shamszadeh, M Akrami, S Asgary - Scientific Reports, 2022 - nature.com
Nano-bio interactions are size-dependent. The present study investigates whether core–
shell chitosan-alginate particle size governs biological activities as well as protein release …