Meningiomas are the most common intracranial tumor, making up more than a third of all
primary central nervous system (CNS) tumors. They are mostly benign tumors that can be …

Meningiomas currently are among the most frequent intracranial tumours. Although the
majority of meningiomas can be cured by surgical resection,∼ 20% of patients have an …

Patient-derived xenografts (PDXs) have become a prominent cancer model system, as they
are presumed to faithfully represent the genomic features of primary tumors. Here we …

Background Meningiomas are the most common primary intracranial tumor in adults.
Clinical care is currently guided by the World Health Organization (WHO) grade assigned to …

High-grade meningiomas are associated with neuro-cognitive morbidity and have limited
treatments. High-grade meningiomas harbor an immunosuppressive tumor …

Meningiomas account for one-third of all primary brain tumors. Although typically benign,
about 20% of meningiomas are aggressive, and despite the rigor of the current …

OBJECTIVE Recent large-cohort sequencing studies have investigated the genomic
landscape of meningiomas, identifying somatic coding alterations in NF2, SMARCB1 …

One-fifth of meningiomas classified as benign by World Health Organization (WHO)
histopathological grading will behave malignantly. To better diagnose these tumors, several …

Surgery has long been established as the first-line treatment for the majority of symptomatic
and enlarging meningiomas, and evidence for its success is derived from retrospective case …

Meningiomas are the most common primary intracranial tumors, but the molecular drivers of
meningioma tumorigenesis are poorly understood. We hypothesized that investigating …