Natural inhibitors of PI3K/AKT signaling in breast cancer: emphasis on newly-discovered molecular mechanisms of action

Y Safdari, M Khalili, MA Ebrahimzadeh… - Pharmacological …, 2015 - Elsevier
Epidermal growth factor receptor (EGFR) plays a critical role in the initiation and progression
of a variety of human cancers, including breast cancer. An important signaling pathway …

[HTML][HTML] D-Pinitol—active natural product from carob with notable insulin regulation

A Azab - Nutrients, 2022 - mdpi.com
Carob is one of the major food trees for peoples of the Mediterranean basin, but it has also
been traditionally used for medicinal purposes. Carob contains many nutrients and active …

[HTML][HTML] D-pinitol, a highly valuable product from carob pods: Health-promoting effects and metabolic pathways of this natural super-food ingredient and its derivatives

JI López-Sánchez, DA Moreno… - AIMS agriculture and …, 2018 - aimspress.com
D-pinitol is a natural compound related to the important family of inositols. It can be found
and isolated from many plants, being the active component of ayurvedic remedies such as …

Investigating the protective actions of D-pinitol against arsenic-induced toxicity in PC12 cells and the underlying mechanism

MS Rahaman, M Akter, MM Rahman, MT Sikder… - Environmental …, 2020 - Elsevier
Arsenic is awfully toxic metalloid responsible for many human diseases all over the world.
Contrastingly, D-pinitol is a naturally occurring bioactive dietary compound has antioxidant …

Oral administration of lyophilized Dunaliella salina, a carotenoid-rich marine alga, reduces tumor progression in mammary cancer induced rats

R Srinivasan, A Chaitanyakumar, A Mageswari… - Food & function, 2017 - pubs.rsc.org
Dunaliella salina is a photosynthetic cell factory used for the commercial production of food
additives, cattle stock feed and cosmetics as well as active ingredients for pharmaceutical …

Dose response chemopreventive potential of allyl isothiocyanate against 7, 12-dimethylbenz (a) anthracene induced mammary carcinogenesis in female Sprague …

T Rajakumar, P Pugalendhi, S Thilagavathi - Chemico-biological …, 2015 - Elsevier
The present study aimed to investigate the dose response chemopreventive potential of allyl
isothiocyanate (AITC) against 7, 12-dimethylbenz (a) anthracene (DMBA) induced mammary …

Breast cancer amelioration by Butea monosperma in-vitro and in-vivo

P Karia, KV Patel, SSP Rathod - Journal of ethnopharmacology, 2018 - Elsevier
Ethnopharmacological relevance Butea monosperma belonging to family Fabaceae is used
in the Indian traditional medicine (Ayurveda) for various ailments including abdominal …

Allyl isothiocyanate, a potent chemopreventive agent targets AhR/Nrf2 signaling pathway in chemically induced mammary carcinogenesis

T Rajakumar, P Pugalendhi, S Thilagavathi… - Molecular and Cellular …, 2018 - Springer
In the present study, we investigated the effect of allyl isothiocyanate (AITC) on liver
detoxification signaling pathway in 7, 12-dimethylbenz (a) anthracene (DMBA)-induced …

Potent herbicidal activity of Sapindus mukorossi Gaertn. against Avena fatua L. and Amaranthus retroflexus L.

S Ma, L Fu, S He, X Lu, Y Wu, Z Ma, X Zhang - Industrial Crops and …, 2018 - Elsevier
The evaluation of herbicidal activity and the isolation of plant allelopathic substances can
lead to the discovery of new herbicide. This study has confirmed that the ethanol extract of S …

Intraspecific variability of quantity and chemical composition of ethanolic knotwood extracts along the stems of three industrially important softwood species: Abies …

M Brennan, D Hentges, S Cosgun, S Dumarcay… - Holzforschung, 2021 - degruyter.com
Knotwood of softwood species is rich in secondary metabolites, especially lignans. These
metabolites can be extracted with organic solvents, and are known to be valuable sources of …