[HTML][HTML] A precision environmental health approach to prevention of human disease
Human health is determined by the interaction of our environment with the genome,
epigenome, and microbiome, which shape the transcriptomic, proteomic, and metabolomic …
epigenome, and microbiome, which shape the transcriptomic, proteomic, and metabolomic …
[HTML][HTML] Biomonitoring of inorganic arsenic species in pregnancy
J Ashley-Martin, M Fisher, P Belanger… - Journal of Exposure …, 2023 - nature.com
Exposure assessment of inorganic arsenic is challenging due to the existence of multiple
species, complexity of arsenic metabolism, and variety of exposure sources. Exposure …
species, complexity of arsenic metabolism, and variety of exposure sources. Exposure …
Urinary arsenic metabolism, genetic susceptibility, and their interaction on type 2 diabetes
W Li, Z Li, Y Yan, J Zhang, Q Zhou, C Jia, Y Xu, H Cui… - Chemosphere, 2023 - Elsevier
Growing studies investigated the association of arsenic metabolism with type 2 diabetes
(T2D), however, the epidemiological evidence is inconsistent. In addition, the interaction of …
(T2D), however, the epidemiological evidence is inconsistent. In addition, the interaction of …
Arsenic metabolism, N6AMT1 and AS3MT single nucleotide polymorphisms, and their interaction on gestational diabetes mellitus in Chinese pregnant women
X Liang, G Guo, Y Wang, M Wang, X Chen… - Environmental …, 2023 - Elsevier
Abstract Background Single nucleotide polymorphisms (SNPs) in N6AMT1 and AS3MT are
associated with arsenic (As) metabolism, and efficient As methylation capacity has been …
associated with arsenic (As) metabolism, and efficient As methylation capacity has been …
[HTML][HTML] Determinants of arsenic methylation efficiency and urinary arsenic level in pregnant women in Bangladesh
S Gao, PI Lin, G Mostofa, Q Quamruzzaman… - Environmental …, 2019 - Springer
Background Prenatal inorganic arsenic (iAs) exposure is associated with pregnancy
outcomes. Maternal capabilities of arsenic biotransformation and elimination may influence …
outcomes. Maternal capabilities of arsenic biotransformation and elimination may influence …
Predictive capabilities of in vitro colon bioaccessibility for estimating in vivo relative bioavailability of arsenic from contaminated soils: Arsenic speciation and gut …
N Yin, X Cai, P Wang, R Feng, H Du, Y Fu… - Science of the Total …, 2022 - Elsevier
Arsenic (As) transformation by human gut microbiota has been evidenced to impact As
toxicity and human health. However, little is known about the influence of gut microbiota on …
toxicity and human health. However, little is known about the influence of gut microbiota on …
[HTML][HTML] The methyltransferase N6AMT1 participates in the cell cycle by regulating cyclin E levels
M Mutso, B Brūmele, E Serova, F Väärtnõu, M Suija… - Plos one, 2024 - journals.plos.org
The methyltransferase N6AMT1 has been associated with the progression of different
pathological conditions, such as tumours and neurological malfunctions, but the underlying …
pathological conditions, such as tumours and neurological malfunctions, but the underlying …
[HTML][HTML] Arsenic exposure promotes the emergence of cardiovascular diseases
A large number of studies conducted in the past decade 2010–2020 refer to the impact of
arsenic (As) exposure on cardiovascular risk factors. The arsenic effect on humans is …
arsenic (As) exposure on cardiovascular risk factors. The arsenic effect on humans is …
Association between arsenic (+ 3 oxidation state) methyltransferase gene polymorphisms and arsenic methylation capacity in rural residents of northern China: a …
M Zhang, H Xu, Q Lou, Z Zhang, X Zhang, F Yin… - Archives of …, 2023 - Springer
Arsenic is a toxic metal-like element. The toxic reaction of the body to arsenic is related to
the ability of arsenic methylation metabolism. As the rate-limiting enzyme of arsenic …
the ability of arsenic methylation metabolism. As the rate-limiting enzyme of arsenic …
Influence of AS3MT polymorphisms on arsenic metabolism and liver injury in APL patients treated with arsenic trioxide
J Lu, K Yu, S Fan, W Liu, Z Dong, J Li, X Wang… - Toxicology and Applied …, 2019 - Elsevier
Arsenic-induced side effects limit its application in the treatment of acute promyelocytic
leukemia (APL). We recently demonstrated that AS3MT 14215 (rs3740390) genotypes were …
leukemia (APL). We recently demonstrated that AS3MT 14215 (rs3740390) genotypes were …