Gliomas represent the most common type of malignant brain tumor, among which,
glioblastoma remains a clinical challenge with limited treatment options and dismal …

Glioblastoma (GBM) is the most malignant primary brain tumor without effective therapies.
Since bevacizumab was FDA approved for targeting vascular endothelial growth factor …

Glioblastomas (GBM) are routinely treated with ionizing radiation (IR) but inevitably recur
and develop therapy resistance. During treatment, the tissue surrounding tumors is also …

Gliomas are the most frequent type of tumor in the central nervous system, which exhibit
properties that make their treatment difficult, such as cellular infiltration, heterogeneity, and …

Radiotherapy improves survival for common childhood cancers such as medulloblastoma,
leukemia, and germ cell tumors. Unfortunately, long-term survivors suffer sequelae that can …

Background Glioblastoma (GBM) is a primary brain tumor with a 5-year survival rate of≤
5%. We have shown earlier that GBM-antibody-linked curcumin (CC) and also phytosomal …

Cancer is an important long-term risk for astronauts exposed to protons and high-energy
charged particles during travel and residence on asteroids, the moon, and other planets …

The MET proto-oncogene was first identified in osteosarcoma cells exposed to carcinogens.
Although expressed in many normal cells, MET is overexpressed in many human cancers …

Many cellular models aimed at elucidating cancer biology do not recapitulate pathobiology
including tumor heterogeneity, an inherent feature of cancer that underlies treatment …

Mounting evidence is identifying human cytomegalovirus (HCMV) as a potential oncogenic
virus. HCMV has been detected in glioblastoma multiforme (GB). Herewith, we present the …