Low drug bioavailability, which is mostly a result of poor aqueous drug solubilities and of
inadequate drug dissolution rates, is one of the most significant challenges that …

Carbon dioxide is a clean and versatile solvent for the synthesis and processing of a range
of materials. This review focuses on recent advances in polymer synthesis and processing …

Recent developments on particle formation from polymers using supercritical fluids have
been reviewed with an emphasis on articles published during 2000–2003. First, a brief …

Supercritical carbon dioxide has proved its applicability in the area of polymer processing
due to its unique properties as a temporary plasticizer. One of the differences between …

Replacement of traditional solvents with “environmentally benign” carbon dioxide is
receiving increased attention in pharmaceutical processing. Among the reported …

Major advances in drug delivery and targeting over recent years have highlighted the
limitations of conventional particle formation and pretreatment processes in fine-tuning the …

Polymer microspheres and fibers are formed with a versatile new process, precipitation with
a compressed fluid antisolvent. By spraying a 1 wt.% polystyrene in toluene solution into …

Supercritical fluids have a great potential for wide fields of processes. Extraction processes
with supercritical fluids are established even in industrial scale and become again more …

The rapid expansion of supercritical solutions is a promising new technology for particle
formation. The absence of liquid organic solvents, the mild processing temperatures, and the …

Recent developments in biodegradable particle formation using supercritical fluids and
dense gases have been reviewed with an emphasis on studies of micronizing and …