The genus Trichoderma contains fungi with high relevance for humans, with applications in
enzyme production for plant cell wall degradation and use in biocontrol. Here, we provide a …

Crops can be modified by engineering novel RNA interference (RNAi) pathways that create
small RNA molecules to alter gene expression in crops or plant pests. RNAi can generate …

In eukaryotes, DNA is packaged into chromatin by canonical histone proteins. The
specialized histone H3 variant CENP-A provides an epigenetic and structural basis for …

In animals, replication-coupled histone H3. 1 can be distinguished from replication-
independent histone H3. 3. H3. 3 variants are enriched at active genes and their promoters …

Centromere behavior is specialized in meiosis I, so that sister chromatids of homologous
chromosomes are pulled toward the same side of the spindle (through kinetochore mono …

Mitosis ensures equal genome segregation in the eukaryotic lineage. This process is
facilitated by microtubule attachment to each chromosome via its centromere. In …

Centromeres nucleate the formation of kinetochores and are vital for chromosome
segregation during mitosis. The SNF2 family helicase PICH (Plk1‐interacting checkpoint …

The centromere is the genetic locus that organizes the proteinaceous kinetochore and is
responsible for attachment of the chromosome to the spindle at mitosis and meiosis. In most …

Centromeres are differentiated chromatin domains, present once per chromosome, that
direct segregation of the genome in mitosis and meiosis by specifying assembly of the …

Accurate chromosome segregation requires the interaction of chromosomes with the
microtubules from the mitotic spindle. This interaction is mediated by the macro-molecular …