Epigenetic regulation in breast cancer: Insights on epidrugs
A Kim, K Mo, H Kwon, S Choe, M Park, W Kwak… - Epigenomes, 2023 - mdpi.com
Breast cancer remains a common cause of cancer-related death in women. Therefore,
further studies are necessary for the comprehension of breast cancer and the revolution of …
further studies are necessary for the comprehension of breast cancer and the revolution of …
Epigenetics in congenital heart disease
Embryonic heart development is an intricate process that mainly involves morphogens,
transcription factors, and cardiac genes. The precise spatiotemporal expression of these …
transcription factors, and cardiac genes. The precise spatiotemporal expression of these …
The role of selected epigenetic pathways in cardiovascular diseases as a potential therapeutic target
A Wołowiec, Ł Wołowiec, G Grześk, A Jaśniak… - International Journal of …, 2023 - mdpi.com
Epigenetics is a rapidly developing science that has gained a lot of interest in recent years
due to the correlation between characteristic epigenetic marks and cardiovascular diseases …
due to the correlation between characteristic epigenetic marks and cardiovascular diseases …
Epigenetics and congenital heart diseases
L Linglart, D Bonnet - Journal of Cardiovascular Development and …, 2022 - mdpi.com
Congenital heart disease (CHD) is a frequent occurrence, with a prevalence rate of almost
1% in the general population. However, the pathophysiology of the anomalous heart …
1% in the general population. However, the pathophysiology of the anomalous heart …
Nuclear control of vascular smooth muscle cell plasticity during vascular remodeling
Control of vascular smooth muscle cell (SMC) gene expression is an essential process for
establishing and maintaining lineage identity, contractility, and plasticity. Most mechanisms …
establishing and maintaining lineage identity, contractility, and plasticity. Most mechanisms …
Identification of miR-20b-5p as an inhibitory regulator in cardiac differentiation via TET2 and DNA hydroxymethylation
KX Li, JR Li, SJ Zuo, X Li, XT Chen, PY Xiao, HT Li… - Clinical …, 2024 - Springer
Background Congenital heart disease (CHD) is a prevalent congenital cardiac malformation,
which lacks effective early biological diagnosis and intervention. MicroRNAs, as epigenetic …
which lacks effective early biological diagnosis and intervention. MicroRNAs, as epigenetic …
Reprogramming of DNA methylation patterns mediates perfluorooctane sulfonate-induced fetal cardiac dysplasia
M Qiu, J Chen, M Liu, Y Shi, Z Nie, G Dong, X Li… - Science of The Total …, 2024 - Elsevier
Prenatal exposure to perfluorooctane sulfonate (PFOS) is associated with adverse health
effects, including congenital heart disease, yet the underlying mechanisms remain elusive …
effects, including congenital heart disease, yet the underlying mechanisms remain elusive …
Epigenome rewiring in human pluripotent stem cells
The epigenome plays a crucial role in modulating the activity of regulatory elements, thereby
orchestrating diverse transcriptional programs during embryonic development. Human (h) …
orchestrating diverse transcriptional programs during embryonic development. Human (h) …
Epigenetics in diabetic cardiomyopathy
X Ma, S Mei, Q Wuyun, L Zhou, D Sun, J Yan - Clinical Epigenetics, 2024 - Springer
Diabetic cardiomyopathy (DCM) is a critical complication that poses a significant threat to the
health of patients with diabetes. The intricate pathological mechanisms of DCM cause …
health of patients with diabetes. The intricate pathological mechanisms of DCM cause …
Epigenetic regulation of heart failure
M Deogharia, P Gurha - Current Opinion in Cardiology, 2024 - journals.lww.com
Epigenetic modifications provide a mechanism for responding to stress and environmental
variation, enabling reactions to both external and internal stimuli, and their dysregulation …
variation, enabling reactions to both external and internal stimuli, and their dysregulation …