Recent progress in the science of complex coacervation

CE Sing, SL Perry - Soft Matter, 2020 - pubs.rsc.org
Complex coacervation is an associative, liquid–liquid phase separation that can occur in
solutions of oppositely-charged macromolecular species, such as proteins, polymers, and …

[HTML][HTML] Coacervates as models of membraneless organelles

NA Yewdall, AAM André, T Lu, E Spruijt - Current Opinion in Colloid & …, 2021 - Elsevier
Coacervates are condensed liquid-like droplets, usually formed with oppositely charged
polymeric molecules. They have been studied extensively in colloid and interface science …

How Droplets Can Accelerate Reactions─ Coacervate Protocells as Catalytic Microcompartments

IBA Smokers, BS Visser, AD Slootbeek… - Accounts of Chemical …, 2024 - ACS Publications
Conspectus Coacervates are droplets formed by liquid–liquid phase separation (LLPS) and
are often used as model protocells–primitive cell-like compartments that could have aided …

Multiphase complex coacervate droplets

T Lu, E Spruijt - Journal of the American Chemical Society, 2020 - ACS Publications
Liquid–liquid phase separation plays an important role in cellular organization. Many
subcellular condensed bodies are hierarchically organized into multiple coexisting domains …

50th Anniversary Perspective: A Perspective on Polyelectrolyte Solutions

M Muthukumar - Macromolecules, 2017 - ACS Publications
From the beginning of life with the information-containing polymers until the present era of a
plethora of water-based materials in health care industry and biotechnology, polyelectrolytes …

Polyelectrolyte complex coacervates: Recent developments and new frontiers

AM Rumyantsev, NE Jackson… - Annual Review of …, 2021 - annualreviews.org
Polyelectrolyte complex coacervates represent a wide class of materials with applications
ranging from coatings and adhesives to pharmaceutical technologies. They also underpin …

Phase behavior and salt partitioning in polyelectrolyte complex coacervates

L Li, S Srivastava, M Andreev, AB Marciel… - …, 2018 - ACS Publications
Polyelectrolyte complexes are omnipresent both in nature and in the technological world,
including nucleotide condensates, biological marine adhesives, food stabilizers …

Phosphorylation-mediated RNA/peptide complex coacervation as a model for intracellular liquid organelles

WM Aumiller Jr, CD Keating - Nature chemistry, 2016 - nature.com
Biological cells are highly organized, with numerous subcellular compartments.
Phosphorylation has been hypothesized as a means to control the assembly/disassembly of …

Driving forces for oppositely charged polyion association in aqueous solutions: enthalpic, entropic, but not electrostatic

J Fu, JB Schlenoff - Journal of the American Chemical Society, 2016 - ACS Publications
Driving forces for association between oppositely charged biological or synthetic polymers
in aqueous solution have long been identified as electrostatic in origin. This attraction is …

Sequence and entropy-based control of complex coacervates

LW Chang, TK Lytle, M Radhakrishna… - Nature …, 2017 - nature.com
Biomacromolecules rely on the precise placement of monomers to encode information for
structure, function, and physiology. Efforts to emulate this complexity via the synthetic control …