Advances in COVID-19 mRNA vaccine development

E Fang, X Liu, M Li, Z Zhang, L Song, B Zhu… - Signal transduction and …, 2022 - nature.com
To date, the coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has determined 399,600,607 cases and 5,757,562 …

COVID-19 vaccine development: milestones, lessons and prospects

M Li, H Wang, L Tian, Z Pang, Q Yang… - Signal transduction and …, 2022 - nature.com
With the constantly mutating of SARS-CoV-2 and the emergence of Variants of Concern
(VOC), the implementation of vaccination is critically important. Existing SARS-CoV-2 …

Efficacy and safety of the RBD-dimer–based COVID-19 vaccine ZF2001 in adults

L Dai, L Gao, L Tao, SR Hadinegoro… - New England journal …, 2022 - Mass Medical Soc
Background The ZF2001 vaccine, which contains a dimeric form of the receptor-binding
domain of severe acute respiratory syndrome coronavirus 2 and aluminum hydroxide as an …

Evaluation of the safety profile of COVID-19 vaccines: a rapid review

Q Wu, MZ Dudley, X Chen, X Bai, K Dong, T Zhuang… - BMC medicine, 2021 - Springer
Background The rapid process of research and development and lack of follow-up time post-
vaccination aroused great public concern about the safety profile of COVID-19 vaccine …

Reactogenicity and immunogenicity after a late second dose or a third dose of ChAdOx1 nCoV-19 in the UK: a substudy of two randomised controlled trials (COV001 …

A Flaxman, NG Marchevsky, D Jenkin, J Aboagye… - The Lancet, 2021 - thelancet.com
Background COVID-19 vaccine supply shortages are causing concerns about compromised
immunity in some countries as the interval between the first and second dose becomes …

Covid‐19 vaccines and variants of concern: a review

I Hadj Hassine - Reviews in medical virology, 2022 - Wiley Online Library
Since the outbreak of coronavirus disease 2019 (Covid‐19) in December 2019, caused by
the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), the number of …

[HTML][HTML] The SARS-CoV-2 mutations versus vaccine effectiveness: New opportunities to new challenges

JA Malik, S Ahmed, A Mir, M Shinde, O Bender… - Journal of infection and …, 2022 - Elsevier
Abstract Background The SARS-CoV-2 coronavirus epidemic is hastening the discovery of
the most efficient vaccines. The development of cost-effective vaccines seems to be the only …

SARS-CoV-2 vaccines based on the spike glycoprotein and implications of new viral variants

D Martínez-Flores, J Zepeda-Cervantes… - Frontiers in …, 2021 - frontiersin.org
Coronavirus 19 Disease (COVID-19) originating in the province of Wuhan, China in 2019, is
caused by the severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2), whose …

The risk of allergic reaction to SARS-CoV-2 vaccines and recommended evaluation and management: a systematic review, meta-analysis, GRADE assessment, and …

M Greenhawt, EM Abrams, M Shaker, DK Chu… - The Journal of Allergy …, 2021 - Elsevier
Concerns for anaphylaxis may hamper severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) immunization efforts. We convened a multidisciplinary group of international …

A comprehensive review of the protein subunit vaccines against COVID-19

M Heidary, VH Kaviar, M Shirani, R Ghanavati… - Frontiers in …, 2022 - frontiersin.org
Two years after severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), in
December 2019, the first infections were identified in Wuhan city of China. SARS-CoV-2 …