Carbon–carbon bond formation is the key reaction for organic synthesis to construct the
carbon framework of organic molecules. The review gives a selection of biocatalytic C–C …

Carbon‐carbon bond formation is among the most challenging transformations in the
organic synthetic chemistry. Enzymes capable to perform this reaction are of great interest …

The present review summarizes recent achievements in enzymatic thiamine catalysis during
the past three years. With well-established enzymes such as BAL, PDC and TK new …

Thiamin diphosphate‐dependent enzymes participate in numerous biosynthetic pathways
and catalyse a broad range of reactions, mainly involving the cleavage and formation of C …

Covering: up to 2013Cofactor-dependent enzymes which need small organic molecule
cofactors to accomplish enzymatic activity are widespread. The number of newly discovered …

Thiamine diphosphate‐dependent enzymes are broadly distributed in all organisms, and
they catalyse a broad range of C–C bond forming and breaking reactions. Enzymes …

The increasing number of biocatalytic reactions implemented in chemical synthesis routes
raises the urgent need for large amounts of enzymes. Hence, new generic methods are …

Chorismate and isochorismate represent an important branching point connecting primary
and secondary metabolism in bacteria, fungi, archaea and plants. Chorismate-and …

Enzymatic substrate promiscuity is more ubiquitous than previously thought, with significant
consequences for understanding metabolism and its application to biocatalysis. This …

Hydroxy-3-pentanone and 3-hydroxy-2-pentanone are flavor molecules present in various
foods, such as cheese, wine, durian, and honey, where they impart buttery, hay-like, and …