Engineering a trypsin-resistant thermophilic α-galactosidase to enhance pepsin resistance, acidic tolerance, catalytic performance, and potential in the food and feed …

C Niu, X Wan - Journal of Agricultural and Food Chemistry, 2020 - ACS Publications
α-Galactosidase has potential applications, and attempts to improve proteolytic resistance of
enzymes have important values. We use a novel strategy for genetic manipulation of a …

Outside‐binding site mutations modify the active site's shapes in neuraminidase from influenza A H1N1

L Tolentino‐Lopez, A Segura‐Cabrera… - …, 2013 - Wiley Online Library
The recent occurrence of 2009 influenza A (H1N1) pandemic as well as others has raised
concern of a far more dangerous outcome should this virus becomes resistant to current …

[HTML][HTML] Multidrug-resistant phenotype and isolation of a Novel SHV- beta-Lactamase variant in a clinical isolate of Enterobacter cloacae

A Bourouis, M Ben Moussa, O Belhadj - Journal of Biomedical Science, 2015 - Springer
Background ESBL-producing bacteria are a clinical problem in the management of diseases
caused by these pathogens. Worldwide, systemic infections with BL enzymes are evolving …

Targeting a cluster of arginine residues of neuraminidase to avoid oseltamivir resistance in influenza A (H1N1): a theoretical study

LRS Gema, LE Tolentino-Lopez… - Journal of molecular …, 2015 - Springer
Following the influenza A (H1N1) pandemic in Mexico and around the world in 2009, the
numbers of oseltamivir-resistant clinical cases have increased through a mechanism that …

Characterisation of the marine bacterium Phaeobacter inhibens: diversification, competition and surface colonisation

M Majzoub - 2017 - unsworks.unsw.edu.au
In the marine environment microbial communities establish close association with living
surfaces forming biofilms analogous to a “second skin” believed to protect the host from …

Genová exprese porinů a beta-laktamáz během účinku beta-laktamových antibiotik v závislosti na velikosti inokula u klinických izolátů Klebsiella pneumoniae

D Hepnar - 2011 - dspace.cuni.cz
Genová exprese genů porinů a beta-laktamáz během účinku beta-laktamových antibiotik a
efekt inokula u klinických izolátů Klebsiella pneumoniae ABSTRAKT V posledních letech …

[引用][C] 军团菌病常用治疗药物的敏感性研究

刘洋敏, 胡朝晖, 朱庆义 - 中国医药指南, 2012