Viability assessment in liver transplantation—what is the impact of dynamic organ preservation?

R Panconesi, M Flores Carvalho, M Mueller… - Biomedicines, 2021 - mdpi.com
Based on the continuous increase of donor risk, with a majority of organs classified as
marginal, quality assessment and prediction of liver function is of utmost importance. This is …

[HTML][HTML] Machine perfusion of donor livers for transplantation: a proposal for standardized nomenclature and reporting guidelines

SA Karangwa, P Dutkowski, P Fontes, PJ Friend… - American journal of …, 2016 - Elsevier
With increasing demand for donor organs for transplantation, machine perfusion (MP)
promises to be a beneficial alternative preservation method for donor livers, particularly …

Transplantation of discarded livers following viability testing with normothermic machine perfusion

H Mergental, RW Laing, AJ Kirkham… - Nature …, 2020 - nature.com
There is a limited access to liver transplantation, however, many organs are discarded
based on subjective assessment only. Here we report the VITTAL clinical trial (ClinicalTrials …

[HTML][HTML] Utilization of livers donated after circulatory death for transplantation–An international comparison

J Eden, RXS Da Silva, M Cortes-Cerisuelo… - Journal of …, 2023 - Elsevier
Background & Aims Liver graft utilization rates are a hot topic due to the worldwide organ
shortage and the increasing number of transplant candidates on waiting lists. Liver perfusion …

A multicentre outcome analysis to define global benchmarks for donation after circulatory death liver transplantation

A Schlegel, M van Reeven, K Croome, A Parente… - Journal of …, 2022 - Elsevier
Background & Aims The concept of benchmarking is established in the field of transplant
surgery; however, benchmark values for donation after circulatory death (DCD) liver …

Evolving trends in machine perfusion for liver transplantation

P Dutkowski, JV Guarrera, J De Jonge… - …, 2019 - gastrojournal.org
The imbalance between grafts available for transplantation and demands has moved the
focus of many investigators on the search for novel strategies to rescue organs, previously …

Design, analysis, and pitfalls of clinical trials using ex situ liver machine perfusion: the international liver transplantation society consensus guidelines

PN Martins, MD Rizzari, D Ghinolfi, I Jochmans… - …, 2021 - journals.lww.com
Design, Analysis, and Pitfalls of Clinical Trials Using Ex S... : Transplantation Design, Analysis,
and Pitfalls of Clinical Trials Using Ex Situ Liver Machine Perfusion: The International Liver …

Outcomes of normothermic machine perfusion of liver grafts in repeat liver transplantation (NAPLES initiative)

A Hann, H Lembach, A Nutu… - British Journal of …, 2022 - academic.oup.com
Background Retransplantation candidates are disadvantaged owing to lack of good-quality
liver grafts. Strategies that can facilitate transplantation of suboptimal grafts into retransplant …

Primary nonfunction of the liver allograft

H Hartog, A Hann, MTPR Perera - Transplantation, 2022 - journals.lww.com
Severe allograft dysfunction, as opposed to the expected immediate function, following liver
transplantation is a major complication, and the clinical manifestations of such that lead to …

Complications in Post-Liver Transplant Patients

C Agostini, S Buccianti, M Risaliti, L Fortuna… - Journal of Clinical …, 2023 - mdpi.com
Liver transplantation (LT) is the treatment of choice for liver failure and selected cases of
malignancies. Transplantation activity has increased over the years, and indications for LT …