Materials for the spine: anatomy, problems, and solutions

BA Frost, S Camarero-Espinosa, EJ Foster - Materials, 2019 - mdpi.com
Disc degeneration affects 12% to 35% of a given population, based on genetics, age,
gender, and other environmental factors, and usually occurs in the lumbar spine due to …

Design requirements for annulus fibrosus repair: review of forces, displacements, and material properties of the intervertebral disk and a summary of candidate …

RG Long, OM Torre, WW Hom… - Journal of …, 2016 - asmedigitalcollection.asme.org
There is currently a lack of clinically available solutions to restore functionality to the
intervertebral disk (IVD) following herniation injury to the annulus fibrosus (AF) …

In Situ Covalent Reinforcement of a Benzene‐1, 3, 5‐Tricarboxamide Supramolecular Polymer Enables Biomimetic, Tough, and Fibrous Hydrogels and Bioinks

S Hafeez, MC Decarli, A Aldana, M Ebrahimi… - Advanced …, 2023 - Wiley Online Library
Synthetic hydrogels often lack the load‐bearing capacity and mechanical properties of
native biopolymers found in tissue, such as cartilage. In natural tissues, toughness is often …

[HTML][HTML] Mechanics of pulmonary airways: linking structure to function through constitutive modeling, biochemistry, and histology

M Eskandari, TM Nordgren, GD O'Connell - Acta biomaterialia, 2019 - Elsevier
Breathing involves fluid-solid interactions in the lung; however, the lack of experimental data
inhibits combining the mechanics of air flow to airway deformation, challenging the …

Elastic, permeability and swelling properties of human intervertebral disc tissues: A benchmark for tissue engineering

DH Cortes, NT Jacobs, JF DeLucca, DM Elliott - Journal of biomechanics, 2014 - Elsevier
The aim of functional tissue engineering is to repair and replace tissues that have a
biomechanical function, ie, connective orthopaedic tissues. To do this, it is necessary to …

Validation and application of an intervertebral disc finite element model utilizing independently constructed tissue-level constitutive formulations that are nonlinear …

NT Jacobs, DH Cortes, JM Peloquin, EJ Vresilovic… - Journal of …, 2014 - Elsevier
Finite element (FE) models are advantageous in the study of intervertebral disc mechanics
as the stress–strain distributions can be determined throughout the tissue and the applied …

Modeling of human intervertebral disc annulus fibrosus with complex multi-fiber networks

F Ghezelbash, AH Eskandari, A Shirazi-Adl… - Acta biomaterialia, 2021 - Elsevier
Collagen fibers within the annulus fibrosus (AF) lamellae are unidirectionally aligned with
alternating orientations between adjacent layers. AF constitutive models often combine two …

Biaxial tension of fibrous tissue: using finite element methods to address experimental challenges arising from boundary conditions and anisotropy

NT Jacobs, DH Cortes… - Journal of …, 2013 - asmedigitalcollection.asme.org
Planar biaxial tension remains a critical loading modality for fibrous soft tissue and is widely
used to characterize tissue mechanical response, evaluate treatments, develop constitutive …

Mechanical factors regulate Annulus Fibrosus (AF) injury repair and remodeling: a review

Z Wang, X Chen, N Chen, H Yan, K Wu… - ACS Biomaterials …, 2023 - ACS Publications
Low back pain is a common chronic disease that can severely affect the patient's work and
daily life. The breakdown of spinal mechanical homeostasis caused by intervertebral disc …

Modeling multiaxial damage regional variation in human annulus fibrosus

A Tamoud, F Zaïri, A Mesbah, F Zaïri - Acta Biomaterialia, 2021 - Elsevier
In the present article, a fully three-dimensional human annulus fibrosus model is developed
by considering the regional variation of the complex structural organization of collagen …