The interactions of chemokines with their G protein-coupled receptors promote the migration
of leukocytes during normal immune function and as a key aspect of the inflammatory …

G protein‐coupled chemokine receptors and their peptidergic ligands are interesting
therapeutic targets due to their involvement in various immune‐related diseases, including …

Chemokines and their receptors control cell migration during development, immune system
responses, and in numerous diseases, including inflammation and cancer. The structural …

Stem cell homing and breast cancer metastasis are orchestrated by the chemokine stromal
cell–derived factor 1 (SDF-1) and its receptor CXCR4. Here, we report the nuclear magnetic …

Chemokines orchestrate leukocyte trafficking and function in health and disease.
Heterophilic interactions between chemokines in a given microenvironment may amplify …

Chemokines have two types of interactions that function cooperatively to control cell
migration. Chemokine receptors on migrating cells integrate signals initiated upon …

Both chemokine oligomerization and binding to glycosaminoglycans (GAGs) are required for
their function in cell recruitment. Interactions with GAGs facilitate the formation of chemokine …

The chemokine CXCL1 and its receptor CXCR2 play a crucial role in host immune response
by recruiting and activating neutrophils for microbial killing at the tissue site. Dysregulation in …

Tyrosine sulfation is a post‐translational modification of secreted and transmembrane
proteins, including many GPCRs such as chemokine receptors. Most chemokine receptors …

Integral membrane proteins, including G protein-coupled receptors (GPCR) and ion
channels, mediate diverse biological functions that are crucial to all aspects of life. The …