Periodontal health, cognitive decline, and dementia: A systematic review and meta‐analysis of longitudinal studies

S Asher, R Stephen, P Mäntylä… - Journal of the …, 2022 - Wiley Online Library
Background Emerging evidence indicates that poor periodontal health adversely impacts
cognition. This review examined the available longitudinal evidence concerning the effect of …

[HTML][HTML] The links between the gut microbiome, aging, modern lifestyle and Alzheimer's disease

S Askarova, B Umbayev, AR Masoud… - Frontiers in cellular …, 2020 - frontiersin.org
Gut microbiome is a community of microorganisms in the gastrointestinal tract. These
bacteria have a tremendous impact on the human physiology in healthy individuals and …

[HTML][HTML] Anti-herpetic medications and reduced risk of dementia in patients with herpes simplex virus infections—a nationwide, population-based cohort study in …

NS Tzeng, CH Chung, FH Lin, CP Chiang, CB Yeh… - …, 2018 - Elsevier
This retrospective cohort study is to investigate the association between herpes simplex
virus (HSV) infections and dementia, and the effects of anti-herpetic medications on the risk …

[HTML][HTML] Association between chronic periodontitis and the risk of Alzheimer's disease: a retrospective, population-based, matched-cohort study

CK Chen, YT Wu, YC Chang - Alzheimer's research & therapy, 2017 - Springer
Background Although recent short-term cross-sectional studies have revealed that chronic
periodontitis (CP) may be a risk factor for increased cognitive impairment in patients with …

Time to test antibacterial therapy in Alzheimer's disease

F Panza, M Lozupone, V Solfrizzi, M Watling… - Brain, 2019 - academic.oup.com
Alzheimer's disease is associated with cerebral accumulation of amyloid-β peptide and
hyperphosphorylated tau. In the past 28 years, huge efforts have been made in attempting to …

Periodontal disease as a possible cause for Alzheimer's disease

AR Kamer, RG Craig, R Niederman… - Periodontology …, 2020 - Wiley Online Library
Approximately 47 million people worldwide have been diagnosed with dementia, 60%‐80%
of whom have dementia of the Alzheimer's disease type. Unfortunately, there is no cure in …

The gut microbiome and Alzheimer's disease: Complex and bidirectional interactions

R Tarawneh, E Penhos - Neuroscience & Biobehavioral Reviews, 2022 - Elsevier
Structural and functional alterations to the gut microbiome, referred to as gut dysbiosis, have
emerged as potential key mediators of neurodegeneration and Alzheimer disease (AD) …

Assessing the role of Porphyromonas gingivalis in periodontitis to determine a causative relationship with Alzheimer's disease

SK Singhrao, I Olsen - Journal of oral microbiology, 2019 - Taylor & Francis
Chronic periodontitis of 10 years' duration is reported to become a twofold risk factor for the
development of Alzheimer's disease (AD). Periodontitis is modifiable, and this fits with the …

[HTML][HTML] Periodontal pathogens and their links to neuroinflammation and neurodegeneration

D Visentin, I Gobin, Ž Maglica - Microorganisms, 2023 - mdpi.com
Pathogens that play a role in the development and progression of periodontitis have gained
significant attention due to their implications in the onset of various systemic diseases …

Alzheimer disease and the periodontal patient: New insights, connections, and therapies

MI Ryder, P Xenoudi - Periodontology 2000, 2021 - Wiley Online Library
Loss of cognitive function in the aging population, particular those with Alzheimer disease,
presents unique challenges to health practitioners. For the dental practitioner these include …