Neurodegenerative disorders are characterized by progressive loss of particular populations
of neurons. Apoptosis has been implicated in the pathogenesis of neurodegenerative …

Dysregulating cellular metabolism is one of the emerging cancer hallmarks. Mitochondria
are essential organelles responsible for numerous physiologic processes, such as energy …

Imidacloprid (IMI) is a neonicotinoid compound widely used in agriculture production,
causing surface water pollution and threatening non-target organisms. The aim of this study …

Taking advantage of endogenous Ca 2+ to upregulate intramitochondrial Ca 2+ level has
become a powerful mean for mitochondrial dysfunction-mediated tumor therapy. However …

The divalent cation calcium (Ca2+) is considered one of the main second messengers
inside cells and acts as the most prominent signal in a plethora of biological processes. Its …

Mitochondria in addition to be a main cellular power station, are involved in the regulation of
many physiological processes, such as generation of reactive oxygen species, metabolite …

Chitin is a popular hemostatic material, but there are still many deficiencies in its ability to
effectively stop bleeding, prevent infection, and fit wounds. Herein, AgNP …

Bcl-2 family proteins are considered as one of the major regulators of apoptosis. Indeed, this
family is known to control the mitochondrial outer membrane permeabilization (MOMP): a …

Mitochondria are dynamic organelles involved in numerous physiological functions. Beyond
their function in ATP production, mitochondria regulate cell death, reactive oxygen species …

Members of the Bcl-2-protein family are key controllers of apoptotic cell death. The family is
divided into antiapoptotic (including Bcl-2 itself, Bcl-xL, Mcl-1, etc.) and proapoptotic …