Unsupervised machine learning for exploratory data analysis in imaging mass spectrometry
N Verbeeck, RM Caprioli… - Mass spectrometry …, 2020 - Wiley Online Library
Imaging mass spectrometry (IMS) is a rapidly advancing molecular imaging modality that
can map the spatial distribution of molecules with high chemical specificity. IMS does not …
can map the spatial distribution of molecules with high chemical specificity. IMS does not …
Mass spectrometric imaging for biomedical tissue analysis
K Chughtai, RMA Heeren - Chemical reviews, 2010 - ACS Publications
A mass spectrometer is described as the smallest weighing scale ever used in the world. 1
Mass spectrometry (MS) is a unique technique that has an interdisciplinary nature, which …
Mass spectrometry (MS) is a unique technique that has an interdisciplinary nature, which …
A tutorial on support vector machine-based methods for classification problems in chemometrics
This tutorial provides a concise overview of support vector machines and different closely
related techniques for pattern classification. The tutorial starts with the formulation of support …
related techniques for pattern classification. The tutorial starts with the formulation of support …
Normalization in MALDI-TOF imaging datasets of proteins: practical considerations
SO Deininger, DS Cornett, R Paape, M Becker… - Analytical and …, 2011 - Springer
Normalization is critically important for the proper interpretation of matrix-assisted laser
desorption/ionization (MALDI) imaging datasets. The effects of the commonly used …
desorption/ionization (MALDI) imaging datasets. The effects of the commonly used …
MALDI imaging mass spectrometry for direct tissue analysis: a new frontier for molecular histology
A Walch, S Rauser, SO Deininger, H Höfler - Histochemistry and cell …, 2008 - Springer
Matrix-assisted laser desorption/ionization (MALDI) imaging mass spectrometry (IMS) is a
powerful tool for investigating the distribution of proteins and small molecules within …
powerful tool for investigating the distribution of proteins and small molecules within …
Peptide and protein imaging mass spectrometry in cancer research
MALDI mass spectrometry is able to acquire protein profiles directly from tissue that can
describe the levels of hundreds of distinct proteins. MALDI imaging MS can simultaneously …
describe the levels of hundreds of distinct proteins. MALDI imaging MS can simultaneously …
MALDI imaging mass spectrometry: state of the art technology in clinical proteomics
A decade after its inception, MALDI imaging mass spectrometry has become a unique
technique in the proteomics arsenal for biomarker hunting in a variety of diseases. At this …
technique in the proteomics arsenal for biomarker hunting in a variety of diseases. At this …
Spatial segmentation of mass spectrometry imaging data by combining multivariate clustering and univariate thresholding
Spatial segmentation partitions mass spectrometry imaging (MSI) data into distinct regions,
providing a concise visualization of the vast amount of data and identifying regions of …
providing a concise visualization of the vast amount of data and identifying regions of …
Imaging mass spectrometry of thin tissue sections: a decade of collective efforts
P Chaurand - Journal of proteomics, 2012 - Elsevier
Imaging mass spectrometry (MS) allows to monitor the spatial distribution and abundance of
endogenous and administered compounds present within tissue specimens. Several …
endogenous and administered compounds present within tissue specimens. Several …
Concise representation of mass spectrometry images by probabilistic latent semantic analysis
Imaging mass spectrometry (IMS) is a promising technology which allows for detailed
analysis of spatial distributions of (bio) molecules in organic samples. In many current …
analysis of spatial distributions of (bio) molecules in organic samples. In many current …