Domains and functions of spike protein in Sars-Cov-2 in the context of vaccine design

X Xia - Viruses, 2021 - mdpi.com
The spike protein in SARS-CoV-2 (SARS-2-S) interacts with the human ACE2 receptor to
gain entry into a cell to initiate infection. Both Pfizer/BioNTech's BNT162b2 and Moderna's …

Phylogenomic analyses highlight innovation and introgression in the continental radiations of Fagaceae across the Northern Hemisphere

BF Zhou, S Yuan, AA Crowl, YY Liang, Y Shi… - Nature …, 2022 - nature.com
Northern Hemisphere forests changed drastically in the early Eocene with the diversification
of the oak family (Fagaceae). Cooling climates over the next 20 million years fostered the …

[HTML][HTML] Detailed dissection and critical evaluation of the Pfizer/BioNTech and Moderna mRNA vaccines

X Xia - Vaccines, 2021 - mdpi.com
The design of Pfizer/BioNTech and Moderna mRNA vaccines involves many different types
of optimizations. Proper optimization of vaccine mRNA can reduce dosage required for each …

Extreme genomic CpG deficiency in SARS-CoV-2 and evasion of host antiviral defense

X Xia - Molecular biology and evolution, 2020 - academic.oup.com
Wild mammalian species, including bats, constitute the natural reservoir of betacoronavirus
(including SARS, MERS, and the deadly SARS-CoV-2). Different hosts or host tissues …

Phylogenomics reveals the history of host use in mosquitoes

J Soghigian, C Sither, SA Justi, G Morinaga… - Nature …, 2023 - nature.com
Mosquitoes have profoundly affected human history and continue to threaten human health
through the transmission of a diverse array of pathogens. The phylogeny of mosquitoes has …

Phylogenomics, origin, and diversification of Anthozoans (Phylum Cnidaria)

CS McFadden, AM Quattrini, MR Brugler… - Systematic …, 2021 - academic.oup.com
Anthozoan cnidarians (corals and sea anemones) include some of the world's most
important foundation species, capable of building massive reef complexes that support …

Comparative and phylogenetic analyses of six Kenya Polystachya (Orchidaceae) species based on the complete chloroplast genome sequences

H Jiang, J Tian, J Yang, X Dong, Z Zhong… - BMC Plant …, 2022 - Springer
Abstract Background Polystachya Hook. is a large pantropical orchid genus (c. 240 species)
distributed in Africa, southern Asia and the Americas, with the center of diversity in Africa …

Spatiotemporal Evolution of the Global Species Diversity of Rhododendron

XM Xia, MQ Yang, CL Li, SX Huang… - Molecular Biology …, 2022 - academic.oup.com
Evolutionary radiation is a widely recognized mode of species diversification, but its
underlying mechanisms have not been unambiguously resolved for species-rich …

Spread of West Nile virus and Usutu virus in the German bird population, 2019–2020

U Ziegler, F Bergmann, D Fischer, K Müller, CM Holicki… - Microorganisms, 2022 - mdpi.com
West Nile virus (WNV) and Usutu virus (USUV) are important flaviviruses circulating in
Germany. While USUV was first reported more than 10 years ago, WNV has only reached …

A mitochondrial genome phylogeny of voles and lemmings (Rodentia: Arvicolinae): Evolutionary and taxonomic implications

NI Abramson, SY Bodrov, OV Bondareva… - PLoS …, 2021 - journals.plos.org
Arvicolinae is one of the most impressive placental radiations with over 150 extant and
numerous extinct species that emerged since the Miocene in the Northern Hemisphere. The …