Mast cells are (in) famous for their role in allergic diseases, but the physiological and
pathophysiological roles of this ingenious cell are still not fully understood. Mast cells are …

Chronic spontaneous urticaria (CSU) is defined as recurrent episodes of spontaneous
wheal development and/or angioedema for more than six weeks and at least twice a week …

This update and revision of the international guideline for urticaria was developed following
the methods recommended by Cochrane and the Grading of Recommendations …

Background Chronic spontaneous urticaria (CSU) is inadequately controlled in many
patients and greatly affects quality of life. Remibrutinib, a highly selective, oral, novel …

Objective Immunoglobulin E (IgE) and its receptor, FcɛRI, importantly contribute to the
pathophysiology of chronic spontaneous urticaria (CSU). Recent findings point to a possible …

This systematic review evaluates the efficacy and safety of omalizumab for chronic
spontaneous urticaria (CSU). PubMed, Embase, and Cochrane Library were searched for …

Angioedema (AE), transient localized swelling due to extravasated fluid, is commonly
classified as mast cell mediator-induced, bradykinin-mediated or of unknown cause. AE …

Chronic spontaneous urticaria (CSU) is a frequent and often severely disabling disease. A
large number of studies were performed during the last 2 decades to clarify its pathogenesis …

Bruton's tyrosine kinase (BTK), a member of the Tec kinase family, is critically involved in a
range of immunological pathways. The clinical application of BTK inhibitors for B‐cell …

Background Autoimmune chronic spontaneous urticaria (aiCSU) comes with high disease
activity and poor response to treatment. Recently, elevated levels of IgG anti–thyroid …