Naturally occurring chalcones and their biological activities

Z Rozmer, P Perjési - Phytochemistry reviews, 2016 - Springer
The aim of this review is to summarize the various naturally occurring chalcone compounds
which have been isolated from different plants. Chalcones considered as obligate …

Cellular and molecular mediators of neuroinflammation in the pathogenesis of Parkinson's disease

SV More, H Kumar, IS Kim, SY Song… - Mediators of …, 2013 - Wiley Online Library
Neuroinflammation is a host‐defense mechanism associated with restoration of normal
structure and function of the brain and neutralization of an insult. Increasing …

Cardamonin, a natural flavone, alleviates inflammatory bowel disease by the inhibition of NLRP3 inflammasome activation via an AhR/Nrf2/NQO1 pathway

K Wang, Q Lv, Y Miao, S Qiao, Y Dai, Z Wei - Biochemical pharmacology, 2018 - Elsevier
The present study aimed to evaluate the anti-colitis effect and underlying mechanisms of
cardamonin, a natural flavone isolated from Alpinia katsumadai Hayata. The results showed …

[HTML][HTML] Neuroprotective effects of natural compounds on LPS-induced inflammatory responses in microglia

J An, B Chen, X Kang, R Zhang, Y Guo… - American journal of …, 2020 - ncbi.nlm.nih.gov
Neuroinflammation is one of the main mechanisms involved in the progression of
neurodegeneration. The activation of microglia is the main feature of neuroinflammation …

NF-κB Pathway and Its Inhibitors: A Promising Frontier in the Management of Alzheimer's Disease

BS Sivamaruthi, N Raghani, M Chorawala… - Biomedicines, 2023 - mdpi.com
The nuclear factor kappa B (NF-κB) pathway has emerged as a pivotal player in the
pathogenesis of various diseases, including neurodegenerative illnesses like Alzheimer's …

Cardamonin: A new player to fight cancer via multiple cancer signaling pathways

J Nawaz, A Rasul, MA Shah, G Hussain, A Riaz… - Life sciences, 2020 - Elsevier
Nature's pharmacy has undoubtedly served humans as an affordable and safer health-care
regime for a long times. Cardamonin, a chalconoid present in several plants has been …

[HTML][HTML] Standardized extract of Glehnia Littoralis abrogates memory impairment and neuroinflammation by regulation of CREB/BDNF and NF-κB/MAPK signaling in …

R Balakrishnan, YS Kim, GW Kim, WJ Kim… - Biomedicine & …, 2023 - Elsevier
Mild cognitive impairment is a typical symptom of early Alzheimer's disease (AD). Glehnia
littoralis (G. littoralis), a medicinal halophyte plant commonly used to treat strokes, has been …

[HTML][HTML] Cardamonin from a medicinal herb protects against LPS-induced septic shock by suppressing NLRP3 inflammasome

Z Wang, G Xu, Y Gao, X Zhan, N Qin, S Fu, R Li… - … Pharmaceutica Sinica B, 2019 - Elsevier
Aberrant activation of NLRP3 inflammasome has been implicated in the pathogenesis of
diverse inflammation-related diseases, and pharmacological molecules targeting NLRP3 …

The neuroprotective effects and therapeutic potential of the chalcone cardamonin for Alzheimer's disease

K Barber, P Mendonca, KFA Soliman - Brain Sciences, 2023 - mdpi.com
Neurodegenerative diseases (ND) include a wide range of conditions that result from
progressive damage to the neurons. Alzheimer's disease (AD) is one of the most common …

An overview on cardamonin

LM Goncalves, IM Valente… - Journal of medicinal food, 2014 - liebertpub.com
Cardamonin, as shown by the increasing number of publications, has received growing
attention from the scientific community due to the expectations toward its benefits to human …