Colorectal cancer (CRC) is a global health problem responsible for 10% of all cancer
incidences and 9.4% of all cancer deaths worldwide. The number of new cases increases …

Chemical and enzymatic barriers in the gastrointestinal (GI) tract hamper the oral delivery of
many labile drugs. The GI epithelium also contributes to poor permeability for numerous …

Recent trends in nanoparticles-based oral therapy have led to a proliferation of studies to
enhance solubility, permeability and chemical stability of many drugs. One of the significant …

Targeted oral delivery of a drug via the intestinal lymphatic system (ILS) has the advantages
of protecting against hepatic first‐pass metabolism of the drug and improving its …

Osteoporosis is defined as a systemic skeletal disease characterized by low bone mass and
microarchitectural deterioration of bone tissue, with a consequent increase in bone fragility …

In recent decades, lipid-based nanoparticles (LN) have received considerable attention as
nanoscale delivery systems to improve oral bioavailability of poorly absorbed bioactive …

The aim of this work was to study the influence of process variables on the quality attributes
of pomegranate extract loaded solid lipid nanoparticles (PE-SLNs) using Plackett–Burman …

The aim of this study is to design and evaluate a transdermal delivery system for
alendronate sodium (ALS) loaded with nanocarrier to improve its permeability and prolong …

Background Pomegranate extract (PE) is a natural product with potent antioxidant and
anticancer activity because of its polyphenols content. The main purpose of this study was to …

Amphotericin B (AmB) exhibits potential antileishmanial activity, with only a little rate of
recurrence. However, low bioavailability and severe nephrotoxicity are among the major …