Mesenchymal stromal cells and their secretome: new therapeutic perspectives for skeletal muscle regeneration

M Sandonà, L Di Pietro, F Esposito… - … in bioengineering and …, 2021 - frontiersin.org
Mesenchymal stromal cells (MSCs) are multipotent cells found in different tissues: bone
marrow, peripheral blood, adipose tissues, skeletal muscle, perinatal tissues, and dental …

Characteristics and therapeutic potential of human amnion-derived stem cells

QW Liu, QM Huang, HY Wu, GSL Zuo, HC Gu… - International journal of …, 2021 - mdpi.com
Stem cells including embryonic stem cells (ESCs), induced pluripotent stem cells (iPSCs)
and adult stem cells (ASCs) are able to repair/replace damaged or degenerative tissues and …

Autophagy: a potential key contributor to the therapeutic action of mesenchymal stem cells

S Ceccariglia, A Cargnoni, AR Silini, O Parolini - Autophagy, 2020 - Taylor & Francis
Macroautophagy/autophagy occurs at basal levels in all eukaryotic cells and plays an
important role in maintaining bio-energetic homeostasis through the control of molecule …

The long path of human placenta, and its derivatives, in regenerative medicine

AR Silini, A Cargnoni, M Magatti, S Pianta… - … in bioengineering and …, 2015 - frontiersin.org
In the 1800s, a baby born with a caul, a remnant of the amniotic sack or fetal membranes,
was thought to be lucky, special, or protected. Over time, fetal membranes lost their …

The immunomodulatory properties of the human amnion-derived mesenchymal stromal/stem cells are induced by INF-γ produced by activated lymphomonocytes and …

M Bulati, V Miceli, A Gallo, G Amico… - Frontiers in …, 2020 - frontiersin.org
Human mesenchymal stromal/stem cells (MSCs), being immunoprivileged and having
immunomodulatory ability, represent a promising tool to be applied in the field of …

Mesenchymal stem/stromal cells: a new''cells as drugs''paradigm. Efficacy and critical aspects in cell therapy

L de Girolamo, E Lucarelli, G Alessandri… - Current …, 2013 - ingentaconnect.com
Mesenchymal stem cells (MSCs) were first isolated more than 50 years ago from the bone
marrow. Currently MSCs may also be isolated from several alternative sources and they …

Amniotic membrane-mesenchymal stromal cells secreted factors and extracellular vesicle-miRNAs: Anti-inflammatory and regenerative features for musculoskeletal …

E Ragni, A Papait, C Perucca Orfei… - Stem Cells …, 2021 - academic.oup.com
Human amniotic membrane-derived mesenchymal stromal cells (hAMSCs) are easily
obtained in large quantities and free from ethical concerns. Promising therapeutic results for …

Human PMSCs-derived small extracellular vesicles alleviate neuropathic pain through miR-26a-5p/Wnt5a in SNI mice model

Y Lu, J Zhang, F Zeng, P Wang, X Guo, H Wang… - Journal of …, 2022 - Springer
Abstract Background Mesenchymal stem cell (MSCs)-derived small Extracellular Vesicles
(sEVs) are considered as a new cell-free therapy for pain caused by nerve injury, but …

The immunomodulatory properties of amniotic cells: the two sides of the coin

M Magatti, E Vertua, A Cargnoni, A Silini… - Cell …, 2018 - journals.sagepub.com
Among the many cell types useful in developing therapeutic treatments, human amniotic
cells from placenta have been proposed as valid candidates. Both human amniotic epithelial …

Amniotic membrane mesenchymal cells-derived factors skew T cell polarization toward Treg and downregulate Th1 and Th17 cells subsets

S Pianta, P Bonassi Signoroni, I Muradore… - Stem Cell Reviews and …, 2015 - Springer
We previously demonstrated that cells derived from the mesenchymal layer of the human
amniotic membrane (hAMSC) and their conditioned medium (CM-hAMSC) modulate …