Natural killer cells: potential biomarkers and therapeutic target in autoimmune diseases?

E Gianchecchi, DV Delfino, A Fierabracci - Frontiers in immunology, 2021 - frontiersin.org
Autoimmune diseases recognize a multifactorial pathogenesis, although the exact
mechanism responsible for their onset remains to be fully elucidated. Over the past few …

Natural killer cells in systemic autoinflammatory diseases: a focus on systemic juvenile idiopathic arthritis and macrophage activation syndrome

J Vandenhaute, CH Wouters, P Matthys - Frontiers in immunology, 2020 - frontiersin.org
Natural killer (NK) cells are innate immune lymphocytes with potent cytolytic and immune-
regulatory activities. NK cells are well-known for their ability to kill infected and malignant …

Human leukocyte antigen and tumor immunotherapy

DH Liu, FF Mou, M An, P Xia - … Journal of Oncology, 2023 - spandidos-publications.com
Malignant tumors seriously endanger human health and life, and restrict economic
development. Human leukocyte antigen (HLA) is the expression product of the human major …

[PDF][PDF] One year in review 2018: Behçet's syndrome

G Hatemi, E Seyahi, I Fresko, R Talarico… - Clin Exp …, 2018 - clinexprheumatol.org
New epidemiologic studies from Poland, Jordan, Algeria, Taiwan and Korea highlight the
geographic differences in incidence, prevalence and clinical features of Behçet's syndrome …

Association of functional polymorphisms of KIR3DL1/DS1 with Behcet's disease

Á Castaño-Núñez, MA Montes-Cano… - Frontiers in …, 2019 - frontiersin.org
Behçet's disease (BD) is an immune-mediated vasculitis related to imbalances between the
innate and adaptive immune response. Infectious agents or environmental factors may …

[HTML][HTML] KIR3DL1/S1 allotypes contribute differentially to the development of Behçet disease

H Petrushkin, PJ Norman, E Lougee… - The Journal of …, 2019 - journals.aai.org
Behçet disease is a chronic, relapsing-remitting autoinflammatory syndrome with a strong
HLA-B* 51 association. In this paper, we describe a human cohort of 267 individuals with …

A comprehensive overview on the genetics of Behcet's disease

M Mahmoudi, S Aslani, A Meguro… - International Reviews …, 2022 - Taylor & Francis
Behçet's disease (BD) is a systemic and inflammatory disease, characterized mainly by
recurrent oral and genital ulcers, eye involvement, and skin lesions. Although the exact …

Association of killer cell immunoglobulin-like receptor (KIR) genes and their HLA ligands with susceptibility to Takayasu arteritis in the Iranian population

F Beigmohammadi, S Aslani, H Kavosi… - Iranian Journal of …, 2023 - ijaai.tums.ac.ir
Takayasu arteritis (TA) is a chronic inflammatory disorder characterized by vascular damage
and fibrosis in the intima that commonly occurs in the aorta. In many damaged sites in TA …

The investigation of killer-cell immunoglobulin-like receptors (KIRs) and their HLA ligands in Iranian patients with myasthenia gravis.

M Jalalvand, F Beigmohammadi, S Soltani… - Clinical Neurology and …, 2024 - Elsevier
Background Myasthenia gravis (MG) is a disabling disease with the underlying
pathophysiology of auto-antibodies attacking the postsynaptic acetylcholine receptors of …

Toll-like receptor 9 (TLR9) genetic variants rs187084 and rs352140 confer protection from Behcet's disease among Iranians

Z Tadayon, SA Shahzadeh Fazeli, N Gholijani… - BMC rheumatology, 2024 - Springer
Background Behcet's disease (BD) is a multisystem and multifactorial autoimmune disease
characterized by relapsing episodes of oral aphthae, genital ulcers, and ocular and skin …