Background The rapidly expanding clinical adaptation of prostate-specific membrane
antigen (PSMA)-targeted PET imaging in the evaluation of patients with prostate cancer has …

Prostate cancer is the second most common cause of malignancy among men, with bone
metastasis being a significant source of morbidity and mortality in advanced cases …

Purpose To compare the accuracy of 18 F-FACBC and 11 C-choline PET/CT in patients
radically treated for prostate cancer presenting with biochemical relapse. Methods This …

Prostate cancer is the second most common cancer in men worldwide, with a wide spectrum
of biologic behavior ranging from indolent low-risk disease to highly aggressive castration …

PET is a functional imaging method that can exploit various aspects of tumor biology to
enable greater detection of prostate cancer than can be provided by morphologic imaging …

A mild and selective photocatalytic C–H 18F-fluorination reaction has been developed that
provides direct access to 18F-fluorinated amino acids. The biodistribution and uptake of …

Background Positron emission tomography/computed tomography (PET/CT) has recently
emerged as a promising diagnostic imaging platform for prostate cancer. Several …

Prostate cancer is the most common noncutaneous malignancy among men in the Western
world. The natural history and clinical course of prostate cancer are markedly diverse …

Side chain-fluorinated amino acids are useful tools in medicinal chemistry and protein
science. In this review, we outline some general strategies for incorporating fluorine atom (s) …

Fluorine 18 (18F) fluciclovine (anti-1-amino-3–18F-fluorocyclobutane-1-carboxylic acid
[FACBC]) is a radiolabeled amino acid analog that takes advantage of the amino acid …