This review proposes that physical inactivity could be considered a behavior selected by
evolution for resting, and also selected to be reinforcing in life-threatening situations in …

Chronic diseases are major killers in the modern era. Physical inactivity is a primary cause
of most chronic diseases. The initial third of the article considers: activity and prevention …

Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease and
represents the hepatic expression of several metabolic abnormalities of high epidemiologic …

Sedentarism is the pandemic of modern times. It is associated with several medical
conditions including obesity, type 2 diabetes mellitus, cardiovascular diseases and also liver …

BACKGROUND & AIMS: Exercise is an integral component of lifestyle intervention aimed at
weight loss, but an independent benefit of exercise in NAFLD has also been suggested …

BACKGROUND & AIMS: In this study, we sought to determine the temporal relationship
between hepatic mitochondrial dysfunction, hepatic steatosis and insulin resistance, and to …

Although it is no longer debatable that sedentary behaviors are an actual cause of many
metabolic diseases, the physiology of physical inactivity has been poorly investigated for this …

Metabolic dysfunction-associated fatty liver disease (MAFLD) is among the most widespread
metabolic disease globally, and its associated complications including insulin resistance …

Background There is increasing use of high intensity, interval type exercise training in the
management of many lifestyle-related diseases. Purpose To test the hypothesis that …

Objective Endurance exercise training reduces insulin resistance, adipose tissue
inflammation and non-alcoholic fatty liver disease (NAFLD), an effect often associated with …