Recent updates in antimicrobial stewardship in outpatient parenteral antimicrobial therapy

MV Mahoney, LM Childs-Kean, P Khan… - Current Infectious …, 2021 - Springer
Abstract Purpose of Review Antimicrobial stewardship within acute care is common and has
been expanding to outpatient areas. Some inpatient antimicrobial stewardship tactics apply …

Stability of antimicrobials in elastomeric pumps: a systematic review

B Fernández-Rubio, P del Valle-Moreno… - Antibiotics, 2021 - mdpi.com
Outpatient parenteral antimicrobial therapy (OPAThttp) programs have become an important
healthcare tool around the world. Portable elastomeric infusion pumps are functional …

State of the management of infections caused by multidrug-resistant Gram-negative organisms

A Yassin, M Huralska, JM Pogue, D Dixit… - Clinical Infectious …, 2023 - academic.oup.com
In the past decade, the prevalence of multidrug-resistant gram-negative (MDR-GN) bacterial
infections has increased significantly, leading to higher rates of morbidity and mortality …

Decreased hospital readmissions after programmatic strengthening of an outpatient parenteral antimicrobial therapy (OPAT) program

G Agnihotri, AE Gross, M Seok, CY Yen… - Antimicrobial …, 2023 - cambridge.org
Objective: To determine whether a structured OPAT program supervised by an infectious
disease physician and led by an OPAT nurse decreased hospital readmission rates and …

Choosing patients over placebos: Oral transitional therapy vs. IV-only therapy for bacteraemia and infective endocarditis

MC Phillips, N Wald-Dickler, K Davar, R Lee… - Clinical Microbiology …, 2023 - Elsevier
Background The belief that antibiotics must be administered intravenously (IV) to treat
bacteraemia and endocarditis has its origins 70 years ago and has engrained itself in the …

Successful integration of clinical pharmacists in an OPAT program: a real-life multidisciplinary circuit

S Ortonobes, A Mujal-Martínez, M de Castro Julve… - Antibiotics, 2022 - mdpi.com
Outpatient parenteral antimicrobial therapy (OPAT) programs encompass a range of
healthcare processes aiming to treat infections at home, with the preferential use of the …

Dalbavancin vs standard of care for Staphylococcus aureus bacteraemia in patients unable to receive outpatient parenteral antimicrobial therapy

JD Frazier, LL Stoudenmire, JL Wagner… - International Journal of …, 2023 - Elsevier
Background This study compared dalbavancin with standard of care (SOC) for patients with
Staphylococcus aureus bacteraemia (SAB) who were unable to receive outpatient …

Evaluation of opportunities for oral antibiotic therapy in bone and joint infections

H Bhagat, MK Sikka, ES Sukerman… - Annals of …, 2023 - journals.sagepub.com
Background: The OVIVA trial suggests oral antibiotics are an alternative to intravenous
antibiotics to treat bone and joint infections (BJI). A shift in practice to treatment with oral …

Outcomes of Outpatient Parenteral Antimicrobial Therapy With Ceftriaxone for Methicillin-Susceptible Staphylococcus aureus Bloodstream Infections—A Single …

Y Hamad, L Connor, TC Bailey… - Open Forum Infectious …, 2020 - academic.oup.com
Background Staphylococcus aureus bloodstream infections (BSIs) are associated with
significant morbidity and mortality. Ceftriaxone is convenient for outpatient parenteral …

Stability Study of Fosfomycin in Elastomeric Pumps at 4° C and 34° C: Technical Bases for a Continuous Infusion Use for Outpatient Parenteral Antibiotic Therapy

A Manca, A Palermiti, J Mula, J Cusato, D Maiese… - Pharmaceutics, 2023 - mdpi.com
Background: Fosfomycin acts against aerobic Gram−/+ bacteria by blocking the synthesis of
peptidoglycan. Its use has been currently re-evaluated for intravenous administration for the …