Cancer stem cells—origins and biomarkers: perspectives for targeted personalized therapies
L Walcher, AK Kistenmacher, H Suo, R Kitte… - Frontiers in …, 2020 - frontiersin.org
The use of biomarkers in diagnosis, therapy and prognosis has gained increasing interest
over the last decades. In particular, the analysis of biomarkers in cancer patients within the …
over the last decades. In particular, the analysis of biomarkers in cancer patients within the …
[HTML][HTML] Circular RNAs in cancer
Circular RNAs (circRNAs) are a class of single-stranded closed RNA molecules that are
formed by precursor mRNA back-splicing or skipping events of thousands of genes in …
formed by precursor mRNA back-splicing or skipping events of thousands of genes in …
CircRNAs and cancer: biomarkers and master regulators
E Arnaiz, C Sole, L Manterola, L Iparraguirre… - Seminars in cancer …, 2019 - Elsevier
Circular RNAs (circRNAs) are a novel class of regulatory RNAs that despite being relatively
abundant have only recently begun to be explored. There are many thousands of genes that …
abundant have only recently begun to be explored. There are many thousands of genes that …
Function and clinical significance of circRNAs in solid tumors
Y Geng, J Jiang, C Wu - Journal of hematology & oncology, 2018 - Springer
Circular RNA (circRNA) is a new type of endogenous non-coding RNAs (ncRNAs). circRNA
regulates gene expression in many biological processes, and it also participates in the …
regulates gene expression in many biological processes, and it also participates in the …
Circular RNAs in hepatocellular carcinoma: biomarkers, functions and mechanisms
Hepatocellular carcinoma (HCC), a leading cause of cancer-related death with high invasive
and metastatic potential, has a low survival rate. To improve the survival and quality of life in …
and metastatic potential, has a low survival rate. To improve the survival and quality of life in …
The emerging role of circRNAs and their clinical significance in human cancers
L Qian, S Yu, Z Chen, Z Meng, S Huang… - Biochimica et Biophysica …, 2018 - Elsevier
Circular RNA (circRNA), a recently discovered subclass of non-coding RNAs (ncRNAs),
forms a covalently closed loop with neither a 5′ cap structure nor a 3′ polyadenylated tail …
forms a covalently closed loop with neither a 5′ cap structure nor a 3′ polyadenylated tail …
[HTML][HTML] Engineering polymer nanoparticles using cell membrane coating technology and their application in cancer treatments: Opportunities and challenges
Nanotechnology has revolutionized cancer drug delivery, and recent research continues to
focus on the development of “one-size-fits-all,” ie,“all-in-one” delivery nanovehicles …
focus on the development of “one-size-fits-all,” ie,“all-in-one” delivery nanovehicles …
Cancer stem cells in hepatocellular carcinoma: intrinsic and extrinsic molecular mechanisms in stemness regulation
Hepatocellular carcinoma (HCC) remains the most predominant type of liver cancer with an
extremely poor prognosis due to its late diagnosis and high recurrence rate. One of the …
extremely poor prognosis due to its late diagnosis and high recurrence rate. One of the …
[PDF][PDF] CircHIPK3 is upregulated and predicts a poor prognosis in epithelial ovarian cancer
N Liu, J Zhang, LY Zhang… - Eur Rev Med Pharmacol …, 2018 - europeanreview.org
OBJECTIVE: CircRNAs have been recently identified as important regulators in tumors
biological functions. However, the clinical significance of circHIPK3 in epithelial ovarian …
biological functions. However, the clinical significance of circHIPK3 in epithelial ovarian …
[HTML][HTML] TV-circRGPD6 nanoparticle suppresses breast cancer stem cell-mediated metastasis via the miR-26b/YAF2 axis
X Lin, W Chen, F Wei, X Xie - Molecular Therapy, 2021 - cell.com
Metastatic tumor is a major contributor to death caused by breast cancer. However, effective
and targeted therapy for metastatic breast cancer remains to be developed. Initially, we …
and targeted therapy for metastatic breast cancer remains to be developed. Initially, we …