The chemistry of lanthanides in biology: recent discoveries, emerging principles, and technological applications
JA Cotruvo Jr - ACS central science, 2019 - ACS Publications
The essential biological role of rare earth elements lay hidden until the discovery in 2011
that lanthanides are specifically incorporated into a bacterial methanol dehydrogenase. Only …
that lanthanides are specifically incorporated into a bacterial methanol dehydrogenase. Only …
Beyond iron: non-classical biological functions of bacterial siderophores
TC Johnstone, EM Nolan - Dalton Transactions, 2015 - pubs.rsc.org
Bacteria secrete small molecules known as siderophores to acquire iron from their
surroundings. For over 60 years, investigations into the bioinorganic chemistry of these …
surroundings. For over 60 years, investigations into the bioinorganic chemistry of these …
The role of iron and siderophores in infection, and the development of siderophore antibiotics
MGP Page - Clinical Infectious Diseases, 2019 - academic.oup.com
Iron is an essential nutrient for bacterial growth, replication, and metabolism. Humans store
iron bound to various proteins such as hemoglobin, haptoglobin, transferrin, ferritin, and …
iron bound to various proteins such as hemoglobin, haptoglobin, transferrin, ferritin, and …
Iron acquisition systems of gram-negative bacterial pathogens define TonB-dependent pathways to novel antibiotics
Iron is an indispensable metabolic cofactor in both pro-and eukaryotes, which engenders a
natural competition for the metal between bacterial pathogens and their human or animal …
natural competition for the metal between bacterial pathogens and their human or animal …
Microbial iron acquisition: marine and terrestrial siderophores
The vast majority of bacteria require iron for growth. 1, 2 Iron is an essential element
required for key biological processes, including amino acid synthesis, oxygen transport …
required for key biological processes, including amino acid synthesis, oxygen transport …
Recent developments in understanding the iron acquisition strategies of gram positive pathogens
JR Sheldon, DE Heinrichs - FEMS microbiology reviews, 2015 - academic.oup.com
Iron is a versatile redox-active catalyst and a required cofactor within a diverse array of
biological processes. To almost all organisms, iron is both essential and potentially toxic …
biological processes. To almost all organisms, iron is both essential and potentially toxic …
Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases
DB Kell - BMC medical genomics, 2009 - Springer
Background The production of peroxide and superoxide is an inevitable consequence of
aerobic metabolism, and while these particular'reactive oxygen species'(ROSs) can exhibit a …
aerobic metabolism, and while these particular'reactive oxygen species'(ROSs) can exhibit a …
Iron in innate immunity: starve the invaders
T Ganz - Current opinion in immunology, 2009 - Elsevier
Iron is essential for nearly all living organisms. Innate immunity effectively restricts iron
availability to microbial invaders. Some microbes have evolved effective countermeasures …
availability to microbial invaders. Some microbes have evolved effective countermeasures …
Inhibition of α-glucosidase and α-amylase by flavonoid glycosides from Lu'an GuaPian tea: molecular docking and interaction mechanism
Green tea may favorably modulate blood glucose homeostasis, and regular consumption of
green tea can prevent the development of type 2 diabetes mellitus. In this study, α …
green tea can prevent the development of type 2 diabetes mellitus. In this study, α …
Iron traffics in circulation bound to a siderocalin (Ngal)–catechol complex
The lipocalins are secreted proteins that bind small organic molecules. Scn-Ngal (also
known as neutrophil gelatinase associated lipocalin, siderocalin, lipocalin 2) sequesters …
known as neutrophil gelatinase associated lipocalin, siderocalin, lipocalin 2) sequesters …