HIV–host cell interactions

SK Masenga, BC Mweene, E Luwaya, L Muchaili… - Cells, 2023 - mdpi.com
The development of antiretroviral drugs (ARVs) was a great milestone in the management of
HIV infection. ARVs suppress viral activity in the host cell, thus minimizing injury to the cells …

Neglected gut microbiome: interactions of the non-bacterial gut microbiota with enteric pathogens

K Jaswal, OA Todd, J Behnsen - Gut Microbes, 2023 - Taylor & Francis
ABSTRACT A diverse array of commensal microorganisms inhabits the human intestinal
tract. The most abundant and most studied members of this microbial community are …

Tumor microenvironment and immune-related therapies of head and neck squamous cell carcinoma

Y Qin, X Zheng, W Gao, B Wang, Y Wu - Molecular Therapy-Oncolytics, 2021 - cell.com
Head and neck squamous cell carcinomas (HNSCCs) are a type of common malignant
tumor, mainly manifesting as oropharyngeal, oral cavity, laryngopharyngeal …

[HTML][HTML] Combining gut microbiota modulation and enzymatic-triggered colonic delivery by prebiotic nanoparticles improves mouse colitis therapy

H Li, Y Cheng, L Cui, Z Yang, J Wang… - Biomaterials …, 2024 - spj.science.org
The efficacy of ulcerative colitis (UC) therapy is closely connected to the composition of gut
microbiota in the gastrointestinal tract. Prebiotic-based nanoparticles (NPs) provide a more …

Altered tryptophan metabolism on the kynurenine pathway in depressive patients with small intestinal bacterial overgrowth

C Chojnacki, P Konrad, A Błońska, M Medrek-Socha… - Nutrients, 2022 - mdpi.com
The causes of depression are diverse and are still not fully understood. Recently, an
increasing role is attributed to nutritional and inflammatory factors. The aim of this study was …

[HTML][HTML] Effects of Combustible Cigarettes and Heated Tobacco Products on Systemic Inflammatory Response in Patients with Chronic Inflammatory Diseases

N Kastratovic, N Zdravkovic, I Cekerevac, V Sekerus… - Diseases, 2024 - mdpi.com
Smoke derived from combustible cigarettes (CCs) contains numerous harmful chemicals
that can impair the viability, proliferation, and activation of immune cells, affecting the …

[HTML][HTML] Metabolic syndrome attenuates ulcerative colitis: Correlation with interleukin-10 and galectin-3 expression

M Jovanovic, BS Markovic, N Gajovic… - World Journal of …, 2019 - ncbi.nlm.nih.gov
BACKGROUND Ulcerative colitis (UC) is a chronic disease characterized by inflammation of
intestinal epithelium, primarily of the colon. An increasing prevalence of metabolic syndrome …

IDO targeting in sarcoma: biological and clinical implications

I Nafia, M Toulmonde, D Bortolotto, A Chaibi… - Frontiers in …, 2020 - frontiersin.org
Sarcomas are heterogeneous malignant mesenchymal neoplasms with limited sensitivity to
immunotherapy. We recently demonstrated an increase in Kynurenine Pathway (KP) activity …

Probiotics in intestinal mucosal healing: a new therapy or an old friend?

E Filidou, G Kolios - Pharmaceuticals, 2021 - mdpi.com
Inflammatory bowel disease (IBD), Crohn's disease, and ulcerative colitis are characterized
by chronic and relapsing inflammation, while their pathogenesis remains mostly …

Current paradigms of tolerogenic dendritic cells and clinical implications for systemic lupus erythematosus

P Ritprajak, C Kaewraemruaen, N Hirankarn - Cells, 2019 - mdpi.com
Tolerogenic dendritic cells (tolDCs) are central players in the initiation and maintenance of
immune tolerance and subsequent prevention of autoimmunity. Recent advances in …