[HTML][HTML] Generation and propagation of radical reactions on proteins

CL Hawkins, MJ Davies - Biochimica et Biophysica Acta (BBA) …, 2001 - Elsevier
The oxidation of proteins by free radicals is thought to play a major role in many oxidative
processes within cells and is implicated in a number of human diseases as well as ageing …

[PDF][PDF] Suicide inactivation of peroxidases and the challenge of engineering more robust enzymes

B Valderrama, M Ayala, R Vazquez-Duhalt - Chemistry & biology, 2002 - cell.com
As the number of industrial applications for proteins continues to expand, the exploitation of
protein engineering becomes critical. It is predicted that protein engineering can generate …

The mechanism of autooxidation of myoglobin.

RE Brantley, SJ Smerdon, AJ Wilkinson… - Journal of Biological …, 1993 - ASBMB
Time courses for the autooxidation of native and mutant sperm whale and pig myoglobins
were measured at 37 degrees C in the presence of catalase and superoxide dismutase. In …

Myoglobin-induced lipid oxidation. A review

CP Baron, HJ Andersen - Journal of agricultural and food …, 2002 - ACS Publications
An overview of myoglobin-initiated lipid oxidation in simple model systems, muscle, and
muscle-based foods is presented. The potential role of myoglobin spin and redox states in …

[PDF][PDF] Lipid oxidation: theoretical aspects

KM Schaich - Bailey's industrial oil and fat products, 2005 - researchgate.net
Many excellent chapters and books have been written on lipid oxidation (1–11). Studies of
lipid oxidation are provided differently by different authors: each scientist studying lipid …

The toxicities of native and modified hemoglobins

J Everse, N Hsia - Free Radical Biology and Medicine, 1997 - Elsevier
Recent research on the potential use of hemoglobin derivatives as a blood substitute has
revealed that the administration of large quantities of free hemoglobin into the circulation …

A causative role for redox cycling of myoglobin and its inhibition by alkalinization in the pathogenesis and treatment of rhabdomyolysis-induced renal failure

KP Moore, SG Holt, RP Patel, DA Svistunenko… - Journal of Biological …, 1998 - ASBMB
Muscle injury (rhabdomyolysis) and subsequent deposition of myoglobin in the kidney
causes renal vasoconstriction and renal failure. We tested the hypothesis that myoglobin …

Redox reactions of hemoglobin and myoglobin: biological and toxicological implications

AI Alayash, RP Patel, RE Cashon - Antioxidants and Redox …, 2001 - liebertpub.com
Direct cytotoxic effects associated with hemoglobin (Hb) or myoglobin (Mb) have been
ascribed to redox reactions (involving either one-or two-electron steps) between the heme …

The redox activity of hemoglobins: from physiologic functions to pathologic mechanisms

BJ Reeder - Antioxidants & redox signaling, 2010 - liebertpub.com
Pentacoordinate respiratory hemoproteins such as hemoglobin and myoglobin have
evolved to supply cells with oxygen. However, these respiratory heme proteins are also …

Metabolomics profiling to determine the effect of postmortem aging on color and lipid oxidative stabilities of different bovine muscles

D Ma, YHB Kim, B Cooper, JH Oh, H Chun… - Journal of Agricultural …, 2017 - ACS Publications
The objective of this study was to identify metabolites that could be associated with oxidative
stability of aged bovine muscles. Three muscles (longissimus lumbrum (LL) …