Post-translational modifications (PTMs) have key roles in extending the functional diversity
of proteins and, as a result, regulating diverse cellular processes in prokaryotic and …

Recent multi-omics studies, including proteomics, transcriptomics, genomics, and
metabolomics have revealed the critical role of post-translational modifications (PTMs) in the …

Phosphorylation of proteins is one of the most significant post-translational modifications
(PTMs) and plays a crucial role in plant functionality due to its impact on signaling, gene …

Abstract Background Metabolic syndrome (MetS) is a prevalent multifactorial disorder that
can increase the risk of developing diabetes, cardiovascular diseases, and cancer. We …

Protein phosphorylation is a key post-translational modification (PTM) that is a central
regulatory mechanism of many cellular signaling pathways. Several protein kinases and …

Prostate cancer (PCa) poses a significant health threat to males, and research has shown
that fish oil (FO) can impede PCa progression by activating multiple mitochondria-related …

Lysine malonylation is one of the most important post-translational modifications (PTMs). It
affects the functionality of cells. Malonylation site prediction in proteins can unfold the …

Phosphorylation is an essential mechanism for regulating protein activities. Determining
kinase-specific phosphorylation sites by experiments involves time-consuming and …

Insulin in the brain is a well-known critical factor in neuro-development and regulation of
adult neurogenesis in the hippocampus. The abnormality of brain insulin signaling is …

Protein ubiquitination is a critical post-translational modification (PTMs) involved in
numerous cellular processes. Identifying ubiquitination sites (Ubi-sites) on proteins offers …