Purpose: To investigate the clinical relevance of macrophages in liver metastasis of
colorectal cancer and their influence on angiogenesis and patient survival. Moreover to …

Targeting angiogenesis through inhibition of the vascular endothelial growth factor (VEGF)
pathway has been successful in the treatment of late stage colorectal cancer. However, not …

The soluble vascular endothelial growth factor (VEGF) receptor 1 (sFLT1) has been tested in
both animals and humans for anti-angiogenic therapies, for example, age-related macular …

Neovascularization can provide tumors with essential nutrients and oxygen, as well as
maintain a microenvironment for tumor cell growth. In this study, we combined anti …

Results: Immunoexpression of p16 was significantly higher in CRC than in adenomas (P=
0.033) and normal colonic mucosa (P= 0.005). There was no statistically significant …

Materials and Methods: A total of 128 CRCs, 50 local nodal metastases, and 42 normal
colonic mucosae were retrieved from the archives at the Department of Pathology at King …

Background and study aims Colorectal carcinoma (CRC) is associated with high morbidity
and mortality. The E-cadherin–catenin complex is crucial in the development and …

Recent evidence demonstrates an essential role of cancer stem cells (CSCs) in cancer
initiation, progression, migration, metastasis as well as chemo-resistance. Nevertheless …

Globally, colorectal cancer (CRC) is in third place in the rank of malignant tumours. In
industrialised countries, CRC is second among causes of death related to malignancy [1] …

The aim of the present study was to identify the target genes of cediranib and the associated
signaling pathways in alveolar soft part sarcoma (ASPS). A microarray dataset (GSE32569) …