[HTML][HTML] Neural control of the lower urinary tract

WC de Groat, D Griffiths… - Comprehensive Physiology, 2015 - ncbi.nlm.nih.gov
This article summarizes anatomical, neurophysiological, pharmacological, and brain
imaging studies in humans and animals that have provided insights into the neural circuitry …

Urothelial signaling

L Birder, KE Andersson - Physiological reviews, 2013 - journals.physiology.org
The urothelium, which lines the inner surface of the renal pelvis, the ureters, and the urinary
bladder, not only forms a high-resistance barrier to ion, solute and water flux, and …

The neural control of micturition

CJ Fowler, D Griffiths, WC De Groat - Nature Reviews Neuroscience, 2008 - nature.com
Micturition, or urination, occurs involuntarily in infants and young children until the age of 3
to 5 years, after which it is regulated voluntarily. The neural circuitry that controls this process …

Epidemiology and pathophysiology of neurogenic bladder after spinal cord injury

R Hamid, MA Averbeck, H Chiang, A Garcia… - World journal of …, 2018 - Springer
Spinal cord injury (SCI) usually affects younger age groups with male preponderance. The
most common traumatic cause is road traffic accident followed by sports accidents and gun …

Physiology and pathophysiology of purinergic neurotransmission

G Burnstock - Physiological reviews, 2007 - journals.physiology.org
This review is focused on purinergic neurotransmission, ie, ATP released from nerves as a
transmitter or cotransmitter to act as an extracellular signaling molecule on both pre-and …

The urothelium: life in a liquid environment

MG Dalghi, N Montalbetti, MD Carattino… - Physiological …, 2020 - journals.physiology.org
The urothelium, which lines the renal pelvis, ureters, urinary bladder, and proximal urethra,
forms a high-resistance but adaptable barrier that surveils its mechanochemical …

DECREASED SENSORY RECEPTORS P2X3 AND TRPV1 IN SUBUROTHELIAL NERVE FIBERS FOLLOWING INTRADETRUSOR INJECTIONS OF BOTULINUM …

A Apostolidis, R Popat, Y Yiangou… - The Journal of …, 2005 - auajournals.org
Purpose: Botulinum neurotoxin type A (BoNT/A) is effective in the treatment of intractable
detrusor overactivity (DO). In addition to its known inhibitory effect on presynaptic release of …

Receptors, channels, and signalling in the urothelial sensory system in the bladder

L Merrill, EJ Gonzalez, BM Girard… - Nature Reviews Urology, 2016 - nature.com
The storage and periodic elimination of urine, termed micturition, requires a complex neural
control system to coordinate the activities of the urinary bladder, urethra, and urethral …

Mechanisms of disease: involvement of the urothelium in bladder dysfunction

LA Birder, WC De Groat - Nature clinical practice Urology, 2007 - nature.com
Although the urinary bladder urothelium has classically been thought of as a passive barrier
to ions and solutes, a number of novel properties have been recently attributed to urothelial …

Afferent nerve regulation of bladder function in health and disease

WC de Groat, N Yoshimura - Sensory nerves, 2009 - Springer
The afferent innervation of the urinary bladder consists primarily of small myelinated (Aδ)
and unmyelinated (C-fiber) axons that respond to chemical and mechanical stimuli …