Epithelial barrier hypothesis: effect of the external exposome on the microbiome and epithelial barriers in allergic disease

Z Celebi Sozener, B Ozdel Ozturk, P Cerci, M Turk… - Allergy, 2022 - Wiley Online Library
Environmental exposure plays a major role in the development of allergic diseases. The
exposome can be classified into internal (eg, aging, hormones, and metabolic processes) …

Epidemiology of asthma in children and adults

SC Dharmage, JL Perret, A Custovic - Frontiers in pediatrics, 2019 - frontiersin.org
Asthma is a globally significant non-communicable disease with major public health
consequences for both children and adults, including high morbidity, and mortality in severe …

The effects of climate change on respiratory allergy and asthma induced by pollen and mold allergens

G d'Amato, HJ Chong‐Neto, OP Monge Ortega… - Allergy, 2020 - Wiley Online Library
The impact of climate change on the environment, biosphere, and biodiversity has become
more evident in the recent years. Human activities have increased atmospheric …

Meteorological conditions, climate change, new emerging factors, and asthma and related allergic disorders. A statement of the World Allergy Organization

G D'Amato, ST Holgate, R Pawankar… - World allergy …, 2015 - Springer
The prevalence of allergic airway diseases such as asthma and rhinitis has increased
dramatically to epidemic proportions worldwide. Besides air pollution from industry derived …

The Melbourne epidemic thunderstorm asthma event 2016: an investigation of environmental triggers, effect on health services, and patient risk factors

F Thien, PJ Beggs, D Csutoros, J Darvall… - The Lancet Planetary …, 2018 - thelancet.com
Background A multidisciplinary collaboration investigated the world's largest, most
catastrophic epidemic thunderstorm asthma event that took place in Melbourne, Australia …

Accumulation of an endogenous inhibitor of nitric oxide synthesis in chronic renal failure

A Leone, S Moncada, P Vallance, A Calver, J Collier - The Lancet, 1992 - Elsevier
Nitric oxide (NO), synthesised from L-arginine, contributes to the regulation of blood
pressure and to host defence. We describe in-vitro and in-vivo evidence that NO synthesis …

The link between fungi and severe asthma: a summary of the evidence

DW Denning, BR O'driscoll… - European …, 2006 - Eur Respiratory Soc
There is current evidence to demonstrate a close association between fungal sensitisation
and asthma severity. Whether such an association is causal remains to be confirmed, but …

High concentrations of biological aerosol particles and ice nuclei during and after rain

JA Huffman, AJ Prenni, PJ DeMott… - Atmospheric …, 2013 - acp.copernicus.org
Bioaerosols are relevant for public health and may play an important role in the climate
system, but their atmospheric abundance, properties, and sources are not well understood …

Mechanism of grass-pollen-induced asthma

C Suphioglu, MB Singh, P Taylor, RB Knox, R Bellomo… - The Lancet, 1992 - Elsevier
Many asthmatics are sensitive to rye-grass pollen, but pollen grains are too large to
penetrate the lower airways. Our aim was to investigate the mechanism by which rye-grass …

Thunderstorm‐related asthma: what happens and why

G D'Amato, C Vitale, M D'Amato… - Clinical & …, 2016 - Wiley Online Library
The fifth report issued by the Intergovernmental Panel on Climate Change forecasts that
greenhouse gases will increase the global temperature as well as the frequency of extreme …