Alzheimer's and Parkinson's disease therapies in the clinic

P Chopade, N Chopade, Z Zhao… - Bioengineering & …, 2023 - Wiley Online Library
Alzheimer's disease (AD) and Parkinson's disease (PD) are the most prevalent
neurodegenerative diseases, affecting millions and costing billions each year in the United …

Nanotechnology's frontier in combatting infectious and inflammatory diseases: prevention and treatment

Y Huang, X Guo, Y Wu, X Chen, L Feng, N Xie… - … and Targeted Therapy, 2024 - nature.com
Inflammation-associated diseases encompass a range of infectious diseases and non-
infectious inflammatory diseases, which continuously pose one of the most serious threats to …

Recent advances in the targeted delivery of paclitaxel nanomedicine for cancer therapy

F Raza, H Zafar, MW Khan, A Ullah, AU Khan… - Materials …, 2022 - pubs.rsc.org
Cancer cases have reached an all-time high in the current era. Thus, there is a need to
develop advanced therapeutic methods that can effectively inhibit the proliferation of …

Smart nanomaterials for cancer diagnosis and treatment

R Singh, A Sharma, J Saji, A Umapathi, S Kumar… - Nano …, 2022 - Springer
Innovations in nanomedicine has guided the improved outcomes for cancer diagnosis and
therapy. However, frequent use of nanomaterials remains challenging due to specific …

Supramolecular hydrogel based post-surgical implant system for hydrophobic drug delivery against glioma recurrence

MV Wanjale, V Sunil Jaikumar… - International Journal …, 2022 - Taylor & Francis
Purpose The brain, protected by the cranium externally and the blood–brain barrier (BBB)
internally, poses challenges in chemotherapy of aggressive brain tumors. Maximal tumor …

Polymers as encapsulating agents and delivery vehicles of enzymes

A da S. Pereira, CPL Souza, L Moraes… - Polymers, 2021 - mdpi.com
Enzymes are versatile biomolecules with broad applications. Since they are biological
molecules, they can be easily destabilized when placed in adverse environmental …

Nanoparticle‐microglial interaction in the ischemic brain is modulated by injury duration and treatment

A Joseph, R Liao, M Zhang… - Bioengineering & …, 2020 - Wiley Online Library
Cerebral ischemia is a major cause of death in both neonates and adults, and currently has
no cure. Nanotechnology represents one promising area of therapeutic development for …

Polymeric nanomaterial strategies to encapsulate and deliver biological drugs: points to consider between methods

X Chen, Y Wu, NT Nguyen, HT Ta - Biomaterials Science, 2023 - pubs.rsc.org
Biological drugs (BDs) play an increasingly irreplaceable role in treating various diseases
such as cancer, and cardiovascular and neurodegenerative diseases. The market share of …

Nanotherapeutic modulation of excitotoxicity and oxidative stress in acute brain injury

R Liao, TR Wood, E Nance - Nanobiomedicine, 2020 - journals.sagepub.com
Excitotoxicity is a primary pathological process that occurs during stroke, traumatic brain
injury (TBI), and global brain ischemia such as perinatal asphyxia. Excitotoxicity is triggered …

Bioenzyme-based nanomedicines for enhanced cancer therapy

M Ding, Y Zhang, J Li, K Pu - Nano convergence, 2022 - Springer
Bioenzymes that catalyze reactions within living systems show a great promise for cancer
therapy, particularly when they are integrated with nanoparticles to improve their …