Robenidine Analogues Are Potent Antimalarials in Drug-Resistant Plasmodium falciparum

A Krollenbrock, Y Li, JX Kelly… - ACS infectious …, 2021 - ACS Publications
Robenidine is a veterinary drug used in the poultry industry to treat coccidiosis caused by
parasites in the Eimeria genus. Though this compound and related aminoguanidines have …

Amino alcohols as potential antibiotic and antifungal leads

JR Baker, PJ Cossar, MAT Blaskovich, AG Elliott… - Molecules, 2022 - mdpi.com
Five focused compound libraries (forty-nine compounds), based on prior studies in our
laboratory were synthesized and screened for antibiotic and anti-fungal activity against S …

Synthesis of 2‐Aminoquinazoline‐ and 2‐Aminopyrimidine‐Fused Hybrid Scaffolds by Copper‐Catalyzed C(sp2)–N Coupling and Cyclization Followed by Oxidation

JP Kwak, PDQ Dao, CS Cho - European Journal of Organic …, 2020 - Wiley Online Library
2‐(2‐Bromoaryl)‐and 2‐(2‐bromovinyl)‐4, 7‐dimethoxybenzimidazoles are coupled and
cyclized with cyanamide as a building block in dimethylformamide in the presence of a …

In Vitro Activity of Robenidine Analogues NCL259 and NCL265 against Gram-Negative Pathogens

H Pi, H Venter, CC Russell, KA Young, A McCluskey… - Antibiotics, 2022 - mdpi.com
Multidrug-resistant (MDR) Gram-negative pathogens, especially Acinetobacter baumannii,
Pseudomonas aeruginosa, Escherichia coli and Enterobacter spp., are recognized by the …

N‐pyridinylbenzamides: an isosteric approach towards new antimycobacterial compounds

D Nawrot, E Suchánková, O Janďourek… - Chemical Biology & …, 2021 - Wiley Online Library
A series of N‐pyridinylbenzamides was designed and prepared to investigate the influence
of isosterism and positional isomerism on antimycobacterial activity. Comparison to …

Investigating pet dogs as a potential source of antimicrobial resistant enteric bacteria and parasites that may impact on human health

BR Knight - 2024 - researchportal.murdoch.edu.au
Domestic dogs are abundant across the globe, with an estimated 700 million dogs
worldwide (1). In Australia, pets are widely regarded as integral family members, with dogs …