New immunotherapeutic approaches for glioblastoma

GI Vázquez Cervantes… - Journal of …, 2021 - Wiley Online Library
Glioblastoma (GBM) is the most common primary malignant brain tumor with a high mortality
rate. The current treatment consists of surgical resection, radiation, and chemotherapy; …

Efficacy and safety of hypofractionated radiotherapy for the treatment of newly diagnosed glioblastoma multiforme: a systematic review and meta-analysis

G Liao, Z Zhao, H Yang, X Li - Frontiers in Oncology, 2019 - frontiersin.org
Background: Hypofractionated radiotherapy (HFR) is sometimes used in the treatment of
glioblastoma multiforme (GBM). The efficacy and safety of HFR is still under investigation …

NRG brain tumor specialists consensus guidelines for glioblastoma contouring

TJ Kruser, WR Bosch, SN Badiyan, JA Bovi… - Journal of neuro …, 2019 - Springer
Introduction NRG protocols for glioblastoma allow for clinical target volume (CTV) reductions
at natural barriers; however, literature examining CTV contouring and the relevant white …

Feasibility of clinical target volume reduction for glioblastoma treated with standard chemoradiation based on patterns of failure analysis

G Minniti, P Tini, M Giraffa, L Capone, G Raza… - Radiotherapy and …, 2023 - Elsevier
Purpose To analyze recurrence patterns in patients with glioblastoma (GBM) after standard
chemoradiation according to different target volume delineation strategies. Methods and …

Glioma consensus contouring recommendations from a MR-Linac International Consortium Research Group and evaluation of a CT-MRI and MRI-only workflow

CL Tseng, J Stewart, G Whitfield, JJC Verhoeff… - Journal of Neuro …, 2020 - Springer
Introduction This study proposes contouring recommendations for radiation treatment
planning target volumes and organs-at-risk (OARs) for both low grade and high grade …

Hypofractionated accelerated radiotherapy (HART) with concurrent and adjuvant temozolomide in newly diagnosed glioblastoma: a phase II randomized trial (HART …

S Mallick, H Kunhiparambath, S Gupta… - Journal of neuro …, 2018 - Springer
Introduction Maximal safe surgical resection followed by adjuvant chemoradiation has been
standard for newly diagnosed glioblastoma multiforme (GBM). Hypofractionated accelerated …

Limited recurrence distance of glioblastoma under modern radiotherapy era

Z Tu, H Xiong, Y Qiu, G Li, L Wang, S Peng - BMC cancer, 2021 - Springer
Background The optimal treatment volume for Glioblastoma multiforme (GBM) is still a
subject of debate worldwide. The current study was aimed to determine the distances …

Spatial distribution of malignant transformation in patients with low-grade glioma

AS Jakola, D Bouget, I Reinertsen, AJ Skjulsvik… - Journal of neuro …, 2020 - Springer
Background Malignant transformation represents the natural evolution of diffuse low-grade
gliomas (LGG). This is a catastrophic event, causing neurocognitive symptoms, intensified …

Long-term follow-up after BCNU wafer implantation in patients with newly diagnosed glioblastoma

I Shibahara, K Miyasaka, A Sekiguchi… - Journal of Clinical …, 2021 - Elsevier
Bis (2-chloroethyl)-1-nitrosourea (BCNU, or Carmustine) wafers are intraoperatively
implantable wafers used to achieve local tumor control. There is scarce data about the …

Evaluation of the impact of magnetic resonance imaging (MRI) on gross tumor volume (GTV) definition for radiation treatment planning (RTP) of inoperable high grade …

O Sager, F Dincoglan, S Demiral… - … Resonance Part A, 2019 - Wiley Online Library
Aim and Background. Inoperable high‐grade gliomas (HGGs) comprise a specific group of
brain tumors portending a very poor prognosis. In the absence of surgical management …