[HTML][HTML] New drugs before, during, and after hematopoietic stem cell transplantation for patients with acute myeloid leukemia

R Mohty, R El Hamed, E Brissot, A Bazarbachi… - …, 2023 - ncbi.nlm.nih.gov
The treatment of acute myeloid leukemia (AML) has evolved over the past few years with the
advent of next-generation sequencing. Targeted therapies alone or in combination with low …

[HTML][HTML] Cellular therapies in older adults with hematological malignancies: A case-based, state-of-the-art review

NR Neuendorff, A Khan, F Ullrich, S Yates… - Journal of Geriatric …, 2024 - Elsevier
Cellular therapies, including autologous stem cell transplant (ASCT), allogeneic
hematopoietic cell transplantation (alloHCT), and chimeric antigen receptor-(CAR-) T cell …

Optimizing outcomes in secondary AML

A Matthews, KW Pratz - Hematology, 2022 - ashpublications.org
Acute myeloid leukemia (AML) secondary to antecedent hematologic disorder or prior
therapeutics for cancer represent a diverse group of leukemias often associated with inferior …

Older adults with newly diagnosed AML: hot topics for the practicing clinician

C Lai, RS Bhansali, EJ Kuo, G Mannis… - American Society of …, 2023 - ascopubs.org
Over the past decade, our understanding of AML pathogenesis and pathophysiology has
improved significantly with mutational profiling. This has led to translational advances in …

[HTML][HTML] Real-world experience with CPX-351 in high-risk acute myeloid leukemia

RM Lemoli, P Montesinos, A Jain - Critical reviews in oncology/hematology, 2023 - Elsevier
Abstract CPX-351, a dual-drug liposomal encapsulation of daunorubicin/cytarabine, was
approved for newly diagnosed therapy-related acute myeloid leukemia (AML) and AML with …

Advancements and Challenges in the Treatment of AML

Y Abaza, C McMahon, JS Garcia - American Society of Clinical …, 2024 - ascopubs.org
The therapeutic arsenal for the management of AML has expanded significantly in recent
years. Before 2017, newly diagnosed AML was treated with either standard cytarabine-and …

[HTML][HTML] Novel insights and therapeutic approaches in secondary AML

G Marconi, M Rondoni, BA Zannetti, I Zacheo… - Frontiers in …, 2024 - ncbi.nlm.nih.gov
Secondary acute myeloid leukemia (sAML) presents as a complex and multifaceted
ensemble of disorders, positioning itself as both a challenge and an intriguing frontier within …

Transplantation and Cellular Therapy for Older Adults—The MSK Approach

RJ Lin, PB Dahi, B Korc-Grodzicki, A Shahrokni… - Current hematologic …, 2024 - Springer
Abstract Purpose of Review Hematologic malignances more commonly affect older
individuals and often present with advanced, higher risk disease than younger patients …

Therapy-related myeloid malignancies in patients with multiple myeloma.

T Kubicki, M Adamska, K Żyłka… - Acta Haematologica …, 2024 - journals.viamedica.pl
The significant advances in the efficacy of myeloma treatment in recent years have brought
greater focus to the issues of long-term therapy complications. Therapy-related myeloid …

Myeloid neoplasms post cytotoxic therapy: epidemiology, pathogenesis outcomes, prognostic factors, and treatment options

J Ma, Y Wang - Annals of Medicine, 2024 - Taylor & Francis
Myeloid neoplasms post cytotoxic therapy (MN-pCT) are a category includes AML, MDS,
and MDS/MPN arising in patients exposed to cytotoxic (DNA-damaging) therapy for an …