MiRNA–mRNA associated with survival in endometrial cancer

X Xu, T Liu, Y Wang, J Fu, Q Yang, J Wu… - Frontiers in genetics, 2019 - frontiersin.org
Although various factors may contribute to its initiation and progression, the etiology and
prognostic factors of endometrial carcinoma (EC) remains not fully understood. We sought to …

Drug repositioning and subgroup discovery for precision medicine implementation in triple negative breast cancer

Z Al-Taie, M Hannink, J Mitchem, C Papageorgiou… - Cancers, 2021 - mdpi.com
Simple Summary The heterogeneity of complicated diseases like cancer negatively affects
patients' responses to treatment. Finding homogeneous subgroups of patients within the …

[HTML][HTML] Krüppel-like factor 7 is a marker of aggressive gastric cancer and poor prognosis

Z Jiang, T Yu, Z Fan, H Yang, X Lin - Cellular Physiology and …, 2017 - karger.com
Background/Aims: Krüppel-like factor (KLF) 7 protein is a member of the KLF transcription
factor family, which plays important roles in regulating the expression of genes involved in …

DLC1 is a prognosis-related biomarker correlated with tumor microenvironment remodeling in endometrial carcinoma

Y Wu, L Zheng, S Chen, C Lv, Y Huang - Frontiers in Oncology, 2022 - frontiersin.org
Background and Aim Deleted in liver cancer 1 (DLC1) is confirmed as a metastasis
suppressor gene in endometrial carcinoma (EC). However, its functional mechanisms …

Genomic interrogation of familial short stature contributes to the discovery of the pathophysiological mechanisms and pharmaceutical drug repositioning

HSC Wong, YJ Lin, HF Lu, WL Liao, CH Chen… - Journal of biomedical …, 2019 - Springer
Background Genetic factors, dysregulation in the endocrine system, cytokine and paracrine
factors are implicated in the pathogenesis of familial short stature (FSS). Nowadays, the …

[PDF][PDF] A clue to potential therapeutic targets: application of integrative medicine and bioinformatics

SL Xia, H Liu, S Mizushima… - Drug Combination …, 2019 - tmrjournals.com
More and more evidence show that the targets of traditional Chinese medicine are a
resource pool that contributes to the modern medicine. A key aspect of medicine research is …

[PDF][PDF] New Insights into Functional Implication of Genetic Variation in Association with Cancer

Y Zhang - Int J Cancer Clin Res, 2016 - pdfs.semanticscholar.org
Investigations of the genetic basis of cancers have identified hundreds of robust risk loci
associated with cancers using largescale, case-control, candidate gene studies as well as …

[引用][C] Explainable artificial intelligence for patient stratification and drug repositioning

Z Al-Taie - 2021 - University of Missouri--Columbia