Recent observations indicate that the cross-sectional area (CSA) of vertebral bodies is on
average 10% smaller in healthy newborn girls than in newborn boys, a striking difference …

Abstract Purpose of Review Epigenetic mechanisms modify gene activity in a stable manner
without altering DNA sequence. They participate in the adaptation to the environment, as …

Malnutrition in early life increases the risk of osteoporosis, but the association of early-life
undernutrition combined with adulthood obesity patterns with low-energy fracture remains …

The effect of birth weight and childhood body mass index (BMI) on adolescents' bone
parameters is not established. The aim of this longitudinal, population based study was to …

Background To identify sensitive periods for the effect of early life growth on childhood bone
mass we compared the associations between weight and length/height velocities from birth …

Adult chronic disorders, such as hypertension, diabetes, osteoporosis, or obesity, represent
an increasing proportion of the global burden of disease. These disorders are the result of …

Background and aim: High prevalence of childhood overweight/obesity is a major health
concern due to related immediate and long-term health problems. Early identification of …

Osteoporosis is a disease characterised by poor bone strength and microarchitecture,
causing bone fragility, which leads to an increased risk of fractures. Although primarily seen …

Introduction: Although there is evidence that measures of bone size, mineralisation and
density are partly inherited, there are scant data available from which to elucidate …

PURPOSE OF REVIEW: Epigenetic mechanisms modify gene activity in a stable manner
without altering DNA sequence. They participate in the adaptation to the environment, as …